Sentences with phrase «immune response during»

Overall, these factors may promote an increased immune response during pregnancy — and that's not necessarily a great thing.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during gammaherpesvirus infection.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during ¿ - herpesviral infection.

However, researchers are still learning how best to implement immunotherapy regimens, making monitoring of the immune response during treatment development and implementation critical to predicting how the modified cells will function, and how the immune system as a whole will react.

Of particular interest is a possible association of temperature - dependent alternative splicing with the immune response during an infection with fever.

He has made major contributions to monitoring patients» immune responses during vaccine therapy and arriving at accurate prognoses.

This may require further investigation into the innate immune responses during viral infection, and the application of this knowledge using hESC / iPSC - based technologies.

The gut microbiota shapes intestinal immune responses during health and disease.

Not exact matches

In addition to being more highly exposed to As, children appear to be far more sensitive to the potential carcinogenic effects of As49, 50 and have a heightened risk for adverse growth, adverse immune response, and adverse neurodevelopmental outcomes,25,51 - 53 even at relatively low levels of exposure.24, 54 Our results indicate that consumption of rice and rice products increases infants» exposure to As and that regulation could reduce As exposure during this critical phase of development.

Nutrient adequacy of exclusive breastfeeding for the term infant during the first six months of life (2002) WHO This document reviews the impact of exclusive breastfeeding in terms of infant growth, immune response, and neurodevelopment.

Dr. Saper's research has explored circuitry of the brain that controls basic functions such as wake - sleep cycles, feeding, and immune response, and how these circuits are disrupted in neurological disorders, such as Parkinson's disease, in sleep disorders such as narcolepsy and sleep apnea, and during aging.

«This adds to the importance of neuroendocrine hormones as key factors in regulating the maternal immune response» during pregnancy.

During the course of the immunizations, as well as four times after two boosters had been given, the researchers drew blood from the mice to follow their immune responses.

Recently infected participants are an important target group for intervention because transmission is particularly likely during this time due to high viral loads, lack of immune response, and potentially elevated rates of risky behaviors.

The researchers also infected pregnant mice that had the receptor for type I interferons with a viral mimic — a bit of genetic material that goads the body to begin its antiviral immune response — to see if the damage happened only during a Zika infection.

The most common form of anemia in the hospital setting is anemia of inflammation, which occurs when the body's immune response is activated during illness or infection.

During the initial phase, a relatively aggressive inflammation response occurs, and several types of cell from the immune system are attracted to the wound.

Flor M. Munoz, M.D., of the Baylor College of Medicine, Houston, and colleagues randomly assigned 48 women to receive the Tdap vaccine (n = 33) or placebo (n = 15) at 30 to 32 weeks» gestation to evaluate the safety and immunogenicity (ability to produce an immune response) of the vaccine administered during pregnancy.

During the 1980s a Soviet bioweapons lab altered a pneumonia - causing bacterium so that in addition to causing respiratory illness, it could also prompt an immune response to myelin, the sheathing on the nerves.

This inflammatory immune response worked so well that many aspects of it have been preserved during the protracted aeons of evolution.

However, these were all of the antibody isotype M (immunoglobulin M, IgM), the earliest antibody type elicited during an acute immune response.

A certain cytokine, or small protein that helps cells communicate during immune responses, can control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to new treatments, according to a study led by Georgia State University.

During the first days of infection, a typical innate immune response will stop the spread.

The scientists conclude that the study reveals an essential function for CTCF in the orchestration of transcriptional changes during the terminal differentiation of B lymphocytes and advances understanding of the mechanisms that regulate the immune response.

The team found that mice lacking CTCF were incapable of generating germinal centers during the immune response.

During chronic inflammation, this immune response gets out of control and can induce organ damage.

Epinephrine is a stress hormone that is released during increased activity of the sympathetic nervous system and it suppresses the immune response.

The results of the Basel research team open up new ways for improving immune responses after vaccination and for preventing harmful immune responses for example during chronic inflammation.

During the study, Moeser compared the histamine responses of mice to two types of stress conditions — psychological and allergic — where the immune system becomes overworked.

A recent study from the UK called LEAP (Learning Early About Peanut allergy) set out to prove that «regular eating of peanut - containing products, when started during infancy, will elicit a protective immune response instead of an allergic immune reaction.»

While the observed differences of the individual steps were mostly modest, mathematical modeling suggested that even small delays in the trafficking of these immune cells will lead to reduced initiation of a WNV - specific antibody - response during the early stages after infection.

Following transmission by mosquitoes, the early specific (also called adaptive) immune response to WNV is thought to be dominated by antibodies, and, consistent with this, the researchers found that older mice had less potent WNV - specific antibody responses during the early phase of infection.

During inflammatory responses due to infection, trauma, or cancer, the body's immune system becomes highly activated in an attempt to fend off invading organisms, foreign bodies, or tumor cells.

In healthy individuals, MDSCs regulate immune responses and tissue repair, and the population of these cells rapidly expands during inflammation, infection and cancer.

New University of Liverpool research reveals that the immune response of farmed chickens does not develop fast enough to fight off Campylobacter during their short lifespan.

During her time as a postdoc studying immune response to cancer at NCI, she met the other founders of NPA and helped build the organization.

In addition, the strain isolated from lions and hyenas during the 1993/1994 epidemic had rare mutations in two viral proteins: the CDV - H protein, which binds to the host cell receptor (called SLAM CD 150) and therefore plays an important role to facilitate viral entry into host cells, and the CDV - V protein, which enables the virus to manipulate the innate immune response of the host.

The study identified that nociceptin has substantial activity in asthma models given before or during an asthma attack — and that a single molecule reduces both the immune response and causes dilation.

I am interested in applying fluorescence lifetime imaging microscopy (FLIM) to study the metabolic activity during immune response to pancreatic cancer in a zebrafish model.

During AIT, the immune system's responses change.

Aug. 9, 2013 — Gaining and losing weight during «yo - yo dieting» may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

IL - 10 can antagonize IL - 12 during induction of inflammatory immune responses 169, 170, 171, 172, 173, 174.

Interestingly, this state of immune tolerance is similar to what happens during pregnancy, and, more specifically, it's been found that the body's response to a tumor is very similar to its response to embryonic tissues.

It is based on the scientific understanding and high - throughput analyses of human immune responses to disease - related proteins in selected populations including elderly with the capability to stay healthy during the aging process.

8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA damage repair pathway 8.55 Karol Kaiser Wnt secretion during nervous system development 9.20 Simona Hankeová The role of Notch signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex host - pathogen interactions through the energy release for the immune response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach for control of signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure

During exposure to food antigens or nonpathogenic microbes, inflammation is absent, which results in immune tolerance — the default response.

We next investigated the parasite load and the immune response in the brains of mice infected with attenuated Type I and Type III parasites during chronic infection.

Although maternal Abs transferred across the placenta are important to protect infants during the first months of life, several reports have indicated that maternal Abs interfere with the development of infant immune responses.

During her residency in Human Genetics at the University of Bonn she pursued her research interest both in immunology and human genetics by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide mechanistic insights to complement genome - wide association studies.

Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy.