Sentences with phrase «immune response gene expression»

In HIV - 2 and capsid - mutated viruses described in the paper, the cDNA gets sensed by the cytosolic sensor cGAS (radar) leading to induction of antiviral and immune response gene expression.

Not exact matches

They found that gene expression is different at 209 sites in chronically lonely people and that many of those changes fit a pattern of elevated immune activation, inflammation, and depressed response to infection.

«We also found that reduced cohesin led to changes in the expression of genes involved in nerve cell development and the response to an immune signaling protein,» corresponding author Toshihide Yamashita says.

When Bordenstein and Brucker compared gene expression patterns in normal and microbe - free offspring, they found significant changes in many of the genes involved in the immune response (Science, doi.org/m87).

The researchers found that the gene expression levels in immune cells changed in response to the macaque's new social rank within 3 months of establishing the new groups, and the cells got better at fighting infection.

For instance, a tumor influences the expression of genes in immune system cells that are involved in the body's response to cancer.

It binds to a type of receptor found in almost every cell in the body and can regulate the expression of genes that deal with immune response.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during ¿ - herpesviral infection.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during gammaherpesvirus infection.

The finding wasn't surprising, Fallin explains — numerous studies have identified abnormal gene expression of immune genes in autism samples and environmental experiences such as prenatal infection or prenatal exposure to pollutants that can ramp up immune responses are risk factors for ASD.

Our technological expertise ranges from the most fundamental approaches to study membrane transport in lymphocytes and dendritic cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis of gene expression and it regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination, human clinical studies in cancer).

For example, when his psoriasis flared up, the expression of genes related to inflammation and other immune responses also increased.

His discoveries include insights into how changes in gene expression affect T cell exhaustion, a waning of immune function that occurs in response to chronic viral infection and cancer.

How can we modulate gene expression to restore / achieve effective immune response to cancer cells?

Interestingly, they found that infection with the Asian strain of Zika virus triggered a stronger innate immune system response than the African strain, including increased expression of the gene TP53.

Highly concentrated EPA / DHA supports the maintenance of healthy tissues and the normal expression of genes involved in the body's balanced immune response.

Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.

Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88 - dependent: role of the innate immune response in Celiac disease.

Thomas KE, Sapone A, Fasano A, Vogel SN.Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88 - dependent: role of the innate immune response in Celiac disease.J Immunol.