Sentences with phrase «immune response to an attack»

Many of the downregulated genes are involved in the immune system — an interesting result given the recent finding that D. sechellia can't mount an immune response to an attack by the parasitoid wasp Asobara tabida.

Immune Response in the Skin and Hair Follicles Another common place for the immune response to attack is the skin, with a characteristic skin lesion called Dermatiformis Herpetiformis (it resembles Herpes) with intense burning, itching and blistering skin rash which is usually symmetrically distributed on the elbows, knees and the buttocks.

Not exact matches

It not only helps to balance out the immune system functions but works as an anti-inflammatory to help calm down the systemic inflammation response in the body, for people like me, whose immune systems think it's a great idea to attack itself!

Unlike other autoimmune diseases, however, doctors know the trigger for coeliac disease: gluten, which provokes an immune response that causes the body to attack itself.

It's the cornerstone of the body's healing response; ensuring that appropriate nourishment and adequate immune activity is delivered to an area that is injured or under attack.

The systemic problem, (i.e. combining an erroneous outcome with the supposition of it being absolutely dependent on hacking), would be that such a feeble response of a national immune system to relatively trifling attacks implies a nation prone to infections.

An immune response, triggered by foreign neural stem cells, could actually help attack tumors, says Evan Snyder, a stem cell biologist at Sanford Burnham Prebys Medical Discovery Institute in San Diego, California, and one of the early pioneers of the idea of using stem cells to attack tumors.

«If we learn how to control dendritic cells, we could strengthen our immune response to infection when needed, or weaken the action of certain immune cells that attack the body's own tissues in autoimmune disease.»

The gene encodes a protein called PD - 1 that normally acts as a check on the cell's capacity to launch an immune response, to prevent it from attacking healthy cells.

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular «off» switch for the inflammatory immune response that contributes to lung - constricting asthma attacks.

In GVHD, donor cells trigger an immune response that attacks normal tissues, leading to a chain reaction of cellular and molecular responses that increase morbidity and mortality in these patients.

Antril is meant to block the action of interleukin - 1, a messenger protein or «cytokine» which triggers immune responses when the body is attacked by microorganisms.

The protein sits on the surface of T cells and helps dampen the activity of the cells after an immune response, but tumors have found ways to hide from T cell attack by flipping on the PD - 1 switch themselves.

Moreover, the CLA supplementation dampened the injurious inflammation — an inappropriate immune attack — without impairing the animals» ability to produce antibodies or launch a healthy immune response to infection.

A new class of drugs called immune checkpoint inhibitors block molecules on T cells that shut down immune response, freeing the immune system to attack tumors.

Research is also underway to understand whether it can elicit a response against tumors that typically don't provoke an immune attack.

Kwak has developed anti-cancer therapeutic vaccines to spark an immune system attack against tumors, but their effectiveness has been hindered by factors such as MDSCs that stifle immune response.

Vitamin D is thought to protect against such attacks by boosting immune responses to respiratory viruses and dampening down harmful airway inflammation.

These alleles are largely specific to each population, and they help in the «fine - tuning» of the immune response to the specific (local) parasites that attack the host in that population.»

Three American groups are trying to «educate» the thymus to prevent T cells attacking the transplanted tissue, without inhibiting other immune response.

These APOBEC3 enzymes are an essential piece of the immune system's response to viral infection, attacking viral DNA to cause disabling mutations.

Yet the success of both depends on doctors being able to manipulate the body's immune system, to prevent organ rejection in one case and the overzealous immune responses which appear to cause asthma attacks in the other.

«We hope to use these findings to make the immune response to vaccines and infections faster and more productive, and slower and less active for autoimmune conditions where the body attacks itself,» Professor Vinuesa said.

The exercise of flying also releases DNA, so bats may have evolved a weak immune response to avoid attacking their own tissue.

Your immune response to the virus can trigger a crisis such as a heart attack or even spiral out of control and kill you.

She is now looking at how the mouse immune system attacks the parasite to see whether the host's response to the infection is the culprit.

In T1D, beta cells are mistakenly attacked by the body's own immune system, and much prior research has focused on ways to prevent this autoimmune response.

The fetal cells» ability to keep the immune response in check is quite potent, he says, and harnessing that ability in adults could lead to new ways to treat autoimmune diseases, in which the body improperly attacks its own cells.

Immunity is key to long - term responses Knowing that the immune system is capable of recognizing distinctive features of cancer cells and launching a T cell attack against those tumor antigens, and that checkpoint blockade removes a roadblock to that attack, it's logical that these drugs should work against many tumor types.

They can also induce responses against normal tissue antigens, leading the immune system to attack normal tissues and cause toxicity in a subset of patients.

As part of the body's normal, healthy immune response to infection, the barrier formed by blood vessel cells temporarily loosens, allowing white blood cells to exit the bloodstream and attack the invading bacteria or virus, Rehman said.

This paper showcased research results from the new DNA - based Zika vaccine that is based on synthetic DNA and gives instructions to the body's immune system to produce antibodies to attack Zika antigens (i.e. bacteria, viruses, and other foreign substances that trigger immune responses from the body.)

This enhances the immune response through multiple mechanisms: by attaching to the myeloma cells, it marks them for destruction, and by attaching to the NK cells, it primes the immune cells to search for and attack the myeloma cells.

Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Auto - immune diseases are caused by an abnormal immune response which causes the immune system to attack and destroy healthy tissues in a person's own body.

In different contexts, viruses appear capable of attacking tumors in a number of different ways — by directly infecting them, by releasing tumor proteins that trigger a broad immune response against the cancer, and by damaging the blood supply tumors need to survive.

«It's logical to do some things like chemotherapy to attack the tumor and some things like immunotherapy to make the host immune response work better,» says Steinman.

Therapeutic vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Therapeutic cancer vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Gautam says eventually this kind of genetic engineering could be used therapeutically in people, to get immune cells to attack tumors, or nerve cells to regenerate — all in response to light.

Results of a study published online this week at Nature show that Carabin «acts like an internal brake to dial down the speed and intensity of an immune response so that it doesn't go too fast or too far, or careen out of control and attack healthy cells,» says Jun O. Liu, Ph.D., professor of pharmacology, neuroscience and oncology at Hopkins.

«Ipilimumab provides a way to overcome one of the most potent barriers to successful cancer immunotherapy — the ability of cancer to selectively suppress the response of immune cells to the cancer and shut down immune attack,» says Lloyd J. Old, M.D., director of the CRI Scientific Advisory Council.

They can attack cancer cells directly, or they can be used to trigger an immune response against the tumor (so - called cancer immunotherapy).

He suggested that these vectors might also create an immune response that could be used more broadly to attack tuberculosis, malaria, hepatitis B, and other viral and nonviral diseases.

One study found that exposure to chronic stress actually changes the activity of the genes of immune cells — making them more likely to attack the body's own tissue and trigger an autoimmune response.

The second risk is how the body responds to this chronic bacterial attack with an immune response and the resulting inflammation.

However, researchers found that the cord blood of preterm infants had higher levels of two types of immune cells: T cells, which attack foreign agents and promote immune response; and antigen - presenting cells, which guide the T cells to the foreign bodies under attack.

Subsequent lab tests revealed that this immune response had been activated specifically to attack the mother's cells.

Although there are many different types of autoimmune diseases and they can affect many different organs, at their core they are all similar in that they are an immune response caused by systemic inflammation that leads your body to attack itself.

Onions have the ability to stimulate immune response, which protects the human body from the attack of harmful fungus and bacteria.