Sentences with phrase «immune response to tumors»
Each of these molecules plays a critical role in enhancing the overall immune response to the tumor.
sciencedaily.com
In this study, we propose to examine the interaction of this virus with the immune system of dogs, including assessing any potential increase in immune response to the tumor.
While higher TIL levels conferred a favorable prognosis in patients with spontaneous immune response to tumor antigens, they were a poor prognostic factor in patients who did not experience an immune response.
«Our findings suggest that genetically altering tumor cells to produce IL - 15 and IL - 15Rα can cause and enhance immune responses to tumor antigens found in these tumor cells and can be used as a vaccine to target these antigens.
Dr. Gnjatic's research focuses on human antigen - specific immune responses to tumor antigens, in an attempt to define new targets for the development of cancer immunotherapies, assess the efficacy of these immunotherapies, and learn why they may fail.
Tumors also release microparticles containing PS, ultimately suppressing immune response to the tumor by keeping the host's immune system busy fighting particles and dead cells.
In this study, we examined the effectiveness of a vaccination targeting tumors that produced IL - 15 and its cell surface receptor called IL - 15R - alpha -LRB--RRB- and examined their ability to up - regulate (or increase) immune responses to tumor antigens,» Morris says.
«Jumbled chromosomes may dampen the immune response to tumors.»
«Even a small amount of infection with oHSV appears to be enough to trigger an immune response to the tumor.»
«We wanted to establish whether we can actually elicit an immune response to a tumor growing within the brain,» explains Burkhard Becher.
Recent scientific breakthroughs in the understanding of the immune response to tumors have led to the identification of cell molecular pathways that control immune response.
The Pexa - Vec virus was originally developed by Michael Mastrangelo, MD, and Edmund Lattime, PhD, of Thomas Jefferson University in Philadelphia, who engineered the harmless vaccinia virus to infect only cancer cells and other rapidly dividing cells, as well as to stimulate immune activity, in hopes of boosting the immune response to tumors.
It will also measure the immune response to tumor cells and characterize the therapeutic consequences of escalating doses of the study drug.
This reinforced the immune response to tumors, fungi and viruses (Gerson 1999).
While this virus was hypothesized to kill osteosarcoma cells through its replication, we have recently recognized the possibility that the virus stimulates an immune response to tumor, in addition to itself.