Another potential problem is that prolonged exposure to the immunoadhesins or the vector itself could lead to
immune responses against them later.
Not exact matches
There is evidence to suggest the gene originally controlled stem cells or
immune response, and was only
later co-opted to defend animals
against rogue cells when they became large and long - lived.
In 2008, he joined the group of Caetano Reis e Sousa at the Cancer Research UK (CRUK) London Research Institute and
later joined the Francis Crick Institute, where he was awarded Marie Curie and EMBO long - term postdoctoral fellowships to investigate innate
immune receptors and signaling pathways that trigger dendritic cell activation and drive T - cell
responses against viruses or tumors.
In their
latest work, reported online in the Journal of Clinical Investigation, the scientists analyzed blood from such mice and identified two types of autoimmune
response directed specifically
against the protein, with the first
response directed by a specialized kind of
immune system cells called T cells and the second by antibodies.