We are particularly interested in leverage our interdisciplinary expertise in polymer chemistry, nanomedicine, drug delivery and immunobiology to innovate new approaches to modulate the tumor microenvironment and enhance cellular
immune responses to cancer vaccines.
Not exact matches
Treatment
vaccines treat an existing
cancer by strengthening the body's natural
immune response to the
cancer.
Principal Investigator John Morris, MD, clinical co-leader of the Molecular Therapeutics and Diagnosis Program for the CCC, co-leader of the UC
Cancer Institute's Comprehensive Lung
Cancer Program, professor in the division of hematology oncology at the UC College of Medicine and UC Health medical oncologist, says a number of antitumor
vaccines have shown promise for causing
immune responses against tumor antigens
to improve patient outcomes.
Cincinnati
Cancer Center (CCC) and UC Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune system, could initiate the immune response to fight c
Cancer Center (CCC) and UC
Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune system, could initiate the immune response to fight c
Cancer Institute researchers have found that a
vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's
immune system, could initiate the
immune response to fight
cancercancer.
Cancer vaccines, engineered to continue to train T cells to mount a strong immune response against your cancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong rece
Cancer vaccines, engineered
to continue
to train T cells
to mount a strong
immune response against your
cancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong rece
cancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong receptors.
A personal
cancer treatment vaccine that targets distinctive «neoantigens» on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana - Farber Cancer Institute and the Broad Institute of MIT and Ha
cancer treatment
vaccine that targets distinctive «neoantigens» on tumor cells has been shown
to stimulate a potent, safe, and highly specific
immune anti-tumor
response in melanoma patients, report scientists from Dana - Farber
Cancer Institute and the Broad Institute of MIT and Ha
Cancer Institute and the Broad Institute of MIT and Harvard.
Despite decades of attempts
to develop effective
cancer treatment
vaccines, they have mostly failed at producing potent antitumor
immune responses.
Researchers are studying how
to use tumour - specific neoantigens in
vaccines to help the body mount an
immune response targeted at the
cancer.
Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these ant
Cancer vaccines are designed
to stimulate an
immune response against tumor - specific or tumor - associated antigens, encouraging the
immune system
to attack
cancer cells bearing these ant
cancer cells bearing these antigens.
This includes utilizing a modified chimpanzee virus as a
vaccine carrier
to induce an
immune response against HIV, and a new therapeutic
vaccine against human papillomavirus (HPV), a leading cause of cervical
cancer.
A new UC San Francisco study has shown that a
cancer - killing («oncolytic») virus currently in clinical trials may function as a
cancer vaccine — in addition
to killing some
cancer cells directly, the virus alerts the
immune system
to the presence of a tumor, triggering a powerful, widespread
immune response that kills
cancer cells far outside the virus - infected region.
Therapeutic
vaccines are designed
to elicit an
immune response against tumor - specific or tumor - associated antigens, encouraging the
immune system
to attack
cancer cells bearing these antigens.
Her work focuses on using RNA
vaccines for Leishmaniasis and prostate
cancer to generate protective or therapeutic
immune responses in mouse models and evaluate in an artificial lymph node system.
The lab also found that apoptotic tumor cells serve as potent instigators of the T cell
immune response and has worked on developing
cancer vaccines to mimic PND tumor immunity.
Therapeutic
cancer vaccines are designed
to elicit an
immune response against tumor - specific or tumor - associated antigens, encouraging the
immune system
to attack
cancer cells bearing these antigens.
Farokhzad and colleagues have considerable expertise with bench -
to - bedside translation of nanotechnologies for medical applications, and foundational work done in part by his team has led
to the development and first in human testing of a targeted nanoparticle capable of controlling drug release for treatment of
cancers, and the first in human testing of a targeted nanoparticle
vaccine capable of orchestrating an
immune response to facilitate smoking cessation and relapse prevention.
Cancer vaccines are designed
to elicit an
immune response against tumor - specific or tumor - associated antigens.
«We have created a potentially much less expensive approach
to making a therapeutic
cancer vaccine that, while targeting a single tumor antigen, generates an
immune response against multiple antigens.