The direct vascularization of the implanted cells is expected to allow for robust and consistent engraftment but will necessitate the use of maintenance
immune suppression therapy.
Used with concomitant maintenance
immune suppression therapy, the PEC - Direct product has the potential of delivering a sustained, functional cure for patients with type 1 diabetes who are at high risk for acute life - threatening complications.
Not exact matches
These cells, in turn, instruct factor - VIII — specific
immune cells to become tolerant to the coagulation protein, resulting in
suppression of misdirected antibody responses to the replacement
therapy — all without affecting the rest of the
immune system.
Treatment with the current standard
therapy, glucocorticoids, can only be used for a short time due to serious side effects leading to fragile bones and
suppression of both the
immune system and growth hormone production.
Whereas Humira alone could have caused the
immune suppression, another possibility is that Humira combined with the TNF - α blocker encoded by the gene
therapy pushed Mohr over the edge.
Although red
therapy light helps to modulate the
immune system, a 2006 study with mice found that over treatment actually resulted in
immune suppression.
It is not available by itself, and has been shown to cause
immune suppression when given in combination with Canine Distemper (Kirk's Current Veterinary
Therapy XI, «Canine and Feline Vaccines,» Philips, Schultz), so I would consider not giving it.