Sentences with phrase «immune system attacks on»

In some cases, the microbes might even be calling in immune system attacks on their competitors, Rawls said.

As infertility is a side effect of thyroid disease, perhaps the immune system attack on the thyroid gland is an effort to help us survive.

Not exact matches

This is the group of genes which act as the immune system markers on cells, protecting them from being attacked by the system's anti-bodies.

Honestly, I've found that our diet + lifestyle keeps our immune system really high, but if there is something coming on, I employ a two - pronged attack: oregano oil and garlic.

This process makes the formula less likely to cause allergic reactions since the baby's immune system won't launch an «attack» on those smaller proteins.

The systemic problem, (i.e. combining an erroneous outcome with the supposition of it being absolutely dependent on hacking), would be that such a feeble response of a national immune system to relatively trifling attacks implies a nation prone to infections.

The work was on the role of interleukin - 1 in the pathology of graft - versus - host disease (GVHD), the mechanism by which the new immune system, which a patient receives as a bone marrow transplant, attacks the patient's body following the transplantation.

The protein puts the immune system's brakes on, keeping its T cells from recognizing and attacking cancer cells, said Dr. Antoni Ribas, the study's principal investigator and a professor of medicine in the division of hematology - oncology at the David Geffen School of Medicine at UCLA.

Armed with this information, researchers are focusing on approaches that stimulate patients» own immune systems to attack their tumour.

Treatments aimed at revving up the immune system's attack on the cancer may be the most promising approach to cancer therapy since combination chemotherapy.

Their findings suggest that therapies based on these compounds could help to treat rheumatoid arthritis, which occurs when the immune system attacks the joints, causing pain and swelling.

Researchers are developing many different versions of CAR - T cell therapies, but the basic premise is the same: Doctors remove a patient's T cells (immune system cells that attack invaders) from a blood sample and genetically modify them to produce artificial proteins on their surfaces.

The disease commonly starts in childhood and causes the body's own immune system to attack and destroy the insulin - producing cells in the pancreas, leaving the patient dependent on life - long insulin injections.

Although some cancers — particularly those that are rife with mutations like lung cancer or melanoma — create more tangible targets on the surface of cells for the immune system to recognize and attack, other malignancies such as prostate and pancreatic cancers have proved more intransigent.

Rather than waiting for an infected person's immune system to produce noticeable amounts of antibodies, the team chose to home in on the bacteria itself — specifically, proteins the bug sheds when attacked by the body's defenses.

The drug's mechanism of action was entirely new: Instead of attacking cancer cells (like chemo), or indiscriminately revving up the immune system (like IL - 2), ipilimumab blocked a single receptor on one type of immune cell.

Because CTLA - 4 acts like a brake on the immune system, it prevents the body's defenses from attacking cancer cells.

The immune system's attack on the cyst can cause the surrounding brain tissue to swell with inflammation.

The genes revealed the array of immune system signaling molecules and steroid hormones taking part in the immune attack on the embryo.

Eventually a tapeworm cyst that can't move on to its adult stage will die; this signals the host's immune system, eliciting a powerful attack and bringing its covert deception to an end.

Allison pioneered immune checkpoint blockade, an approach that treats the immune system, rather than the tumor directly, by blocking molecules on T cells that shut those attack cells down, protecting tumors from immune response.

This form of interference with bacterial gene regulation is also of pharmaceutical interest as it is known that pathogenic bacteria can protect themselves against attack by the immune system and the effect of antibiotics by forming biofilms, for instance on the epithelium of the respiratory system.

Other possible ways to attack pancreatic cancer cells focus on taking away their ability to hide from the immune system.

Mammals are known to fend off viruses with a system based on interferons, signaling proteins made by immune cells that amplify the body's attack on invaders.

Type - 1 diabetes is an autoimmune disease caused by an inappropriate immune - system attack on healthy tissue.

Until now, most researchers have focused on one of two strategies: attacking tumors with antibodies, which activate the innate immune system, or stimulating T cells, which form the backbone of the adaptive immune system.

A new class of drugs called immune checkpoint inhibitors block molecules on T cells that shut down immune response, freeing the immune system to attack tumors.

The virus seems to turn the weapon back on its host by attacking the immune system of the bacterium, leaving the organism open to infection.

Current rheumatoid arthritis treatments focus on intercepting the immune system's misdirected attack on the lining of affected joints to alleviate the debilitating symptoms, reduce inflammation and slow the progression of the disease.

Yet the success of both depends on doctors being able to manipulate the body's immune system, to prevent organ rejection in one case and the overzealous immune responses which appear to cause asthma attacks in the other.

The immune system's attack on the body's own tissue leads to chronic, painful inflammation in the affected joints.

PD1 is a protein on the surface of T cells, the immune system's specialized attack cells, that shuts down immune response.

Tumor cells often secrete chemicals that suppress the immune system, making it difficult for the body to attack tumors on its own.

The team say their findings could also shed light on how inflammation occurs in certain types of autoinflammatory diseases, where the immune system attacks the body's own tissues.

Certain molecules on tumors can serve as targets for attack by cells of the immune system.

In T1D, beta cells are mistakenly attacked by the body's own immune system, and much prior research has focused on ways to prevent this autoimmune response.

In a lupus patient, this could cause the immune system to ramp up its attacks on the body's cells.

ES cells from a 129 mouse, on the other hand, were unable to form teratomas in B6 mice because the animals» immune systems attacked the cells, which they recognized as foreign.

When the immune system nonetheless attacks self - cells, that error has typically been attributed to a signaling problem, either a misspelled sign placed on the cell's doorknob or a misreading by T and B cells on the hunt.

Ludvigsson emphasizes that weight is probably not the only thing that can press the immune system's attack on the insulin - producing beta cells.

Checkpoint blockade: Fewer but stronger results Allison pioneered immune checkpoint blockade, an approach that treats the immune system, rather than the tumor directly, by blocking molecules on T cells that shut those attack cells down, protecting tumors from immune response.

The drugs, ipilimumab (Yervoy ®) and nivolumab (Opdivo ®), made by Bristol - Myers Squibb (BMS), are two immune checkpoint inhibitors that «release the brakes» on the immune system, allowing it to mount a stronger and more effective attack against cancer.

HLA (human leukocyte antigen)- markers on the surface of a body's cell that identify the cell as one's own (as opposed to a foreign cell) and prevent the immune system from attacking itself.

This paper showcased research results from the new DNA - based Zika vaccine that is based on synthetic DNA and gives instructions to the body's immune system to produce antibodies to attack Zika antigens (i.e. bacteria, viruses, and other foreign substances that trigger immune responses from the body.)

In September, the team added to the vaccine regimen a drug called Keytruda that supports the immune system's attack on tumors.

Multiple sclerosis (MS) affects about 2.3 million people worldwide and is thought to be caused by an immune system - mediated attack on the body.

Researchers at Roswell Park Comprehensive Cancer Center have initiated a clinical trial based on a unique two - pronged strategy for arming the immune system to more effectively attack cancer cells.

Since the liver plays a key role in inducing immune tolerance, that protein increases the production of regulatory T cells, suppressing the immune system's attack on the body.

In some patients, however, the grafted immune system fails to mature properly, which can cause serious infection, undesired attacks on healthy tissue or a cancer relapse.

It's not known what triggers the immune system to attack the embryonic stem cells, but the scientists believe it may be a protein that begins to appear on the surface of the cells as they differentiate into more - specialized tissues.