That's why a vitamin C deficiency can mean a reduced resistance against certain pathogens and a higher supply can enhance several
immune system parameters.
Not exact matches
multiparametric analysis of each cell component of the
immune system, either in normal conditions or exposed to pathogens, thanks to around 300 quantitative
parameters
Phenotyping of every cell component of the
immune system either in normal conditions or exposed to pathogens, thanks to around 300 quantitative
parameters.
Complete phenotyping of the mouse
immune system by polychromatic and mass cytometry (CYTOF), thanks to a set of standardised protocols enabling isolation of viable cells from lymphoid and non-lymphoid organs (lung, skin, intestine,...) for labelling using complex ranges of antibodies whose compatibility allows the simultaneous registration of 50 quantitative
parameters at least (size, structure, specific antibodies and cell viability).
It creates customisable and high - scale mouse models of human disease or displaying an abnormality (KI, KO mouse models) and it provides a complete phenotyping characterisation of the
immune system by polychromatic and mass cytometry measuring more than 50 simultaneous quantitative
parameters in standardised conditions.
*** «Perhaps concern over «uncertainty» in complex, adaptive, open
systems should be investigated by inductive generalization from observations of the dynamics of a wide range of such
systems: ecosystems, social
systems, computer
systems,
immune systems, economic
systems... It is curious that the following things are never admitted as «facts about the world,» but here goes: the observer would note of all of these
systems that they undergo oscillations within apparent
parameters and occasionally flip into new regimes; they often demonstrate novel emergence; and that increased forcing, whether of native elements or exotic ones, increases the rates of oscillation and catastrophic shifts, sometimes after a quieter period of sub-threshold build - up.