Sentences with phrase «immune tissues from»

The team thoroughly analyzed blood and immune tissues from HIV - negative donors, HIV - positive individuals treated with ART, and HIV - positive viremic individuals, collected at several institutions around the world.

Not exact matches

Since these procedures typically require a transfer of tissue from one patient to another, physicians must be careful to choose well - matched donors to avoid rejection by the recipient's immune system....

Cilantro is an extreme anti-oxidant immune - booster that helps detoxify the body by loosening them from the tissue, binding to and pulling out toxins and heavy metals.

About 80 % of our immune system resides in our gut, specifically in the GALT (gut - associated lymphoid tissue), which protects the body from invasion of pathogenic bacteria, fungi, and viruses.

This drug (vedolizumab) blocks a specific adhesion molecule on the surface of the T - cell and thereby inhibits immune cells from binding themselves to receptors present in the intestine, preventing the T - cells from penetrating the blood vessels in the intestinal tissue.

Tissue - engineered livers grown from stem cells, say, could have their genetic code altered so that they would be immune to liver - destroying viruses such as hepatitis C.

In a study published in the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assault.

Senior author Madhav Dhodapkar, M.D., the Arthur H. and Isabel Bunker Professor of Medicine and Immunobiology, and chief of Hematology, said the study, using tissue and blood samples from humans and mice, shows that chronic stimulation of the immune system by lipids made in the context of inflammation underlies the origins of at least a third of all myeloma cases.

«When we analyzed tissue samples in the lab, we found that exposing white fat to macrophage cells from the immune system inhibited the transformation.»

Face transplants require a lifetime of immune - suppressing drugs to keep the body from rejecting the tissue.

Fat tissue taken from mice on a high - fat diet rich in omega - 3 fatty acids (right) has fewer inflammatory immune cells (shown in green) than fat tissue taken from mice that did not receive the omega - 3 supplement (left).

However, not only do neural prosthetic devices suffer from immune - system rejection, but most are believed to eventually fail because of a mismatch between the soft brain tissue and the rigid devices.

The scientists transferred gut microbiota from old and young conventional mice to young germ - free mice, and analysed immune responses in their spleen, lymph nodes and tissues in the small intestine.

Badylak seemed to be saying that he could replace human tissue with tissue from another species without triggering a virulent immune response — something that medical scientists considered impossible.

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body; in other words, the body attacks its own cells.

Thus, replacement tissues made from them shouldn't trigger the immune system rejection that dooms many transplants.

Critics have long argued that transplanting animal tissue into even a small number of immune - suppressed patients could allow obscure pathogens to jump from animals to humans.

The cocaine vaccine works the same way other vaccines do: by stimulating the immune system to produce antibodies that bind to a foreign entity, preventing it from entering the brain or otherwise interacting with the body's organs and tissues.

«This approach is especially attractive because the tissues obtained would be «personalized» and, because of their genetic identity to the patient from whom they were derived, this approach may ultimately lead to tissue replacement without the need for suppression of the immune system.»

Memory T - cells are the cells that become primed to mount a specific immune response when an antigen from a pathogen or injured tissue appears a second time.

Indeed, cancers have been described as «wounds that do not heal» due to their ability to masquerade as damaged tissue in order to receive help from the immune system.

Tuberculosis (TB) tricks the immune system into attacking the body's lung tissue so the bacteria are allowed to spread to other people, new research from the University of Southampton suggests.

To help the new organ withstand the assault from the recipient's natural defenses, doctors developed tissue type matching, a technique to determine if the chemistry of the donor's immune system, defined by antigens on the surface of cells, was similar to that of the recipient's.

In a new study, researchers demonstrate for the first time that recovery from bacterial pneumonia changes the tissue that was infected, seeding the lungs with immune cells called resident memory T (TRM) cells.

Supporting that notion, he found in tissue studies that secretions of those cells could keep immune cells from making IL - 17.

«We've demonstrated definitively that, once the cells are differentiated, the immune response to iPS - derived cells is indistinguishable from its response to unmodified tissue derived from elsewhere in the body,» said Kooreman.

Two teams of scientists suggest that activating immune cells in fat can convert the tissue from a type of fat that stores energy to one that burns it, opening up potential new therapies for obesity and diabetes.

The main role here is played by immune cells migrating from the blood into the tissue to fight the inflammation.

The vesicles travel from the bacteria into the tissue of the host, where they interact with the immune cells.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

It occurs when immune system cells from the donor proliferate and attack the host's tissues.

To eliminate the problem for good, Faustman borrowed an idea from the transplant specialists, who have found that liver or spleen cells can «reeducate» a graft recipient's immune system to treat the graft as native tissue.

Such vaccines could ultimately help people avoid complications in pregnancy and in other medical situations, such as tissue transplants, that benefit from a tempered immune response, he says.

Researchers need to identify cells — possibly adult stem cells from the patient — that can reconstruct lung tissue without provoking attack by the immune system, the problem that plagues current transplant recipients.

Following a tissue graft transplant — such as that of the face, hand, arm or leg — it is standard for doctors to immediately give transplant recipients immunosuppressant drugs to prevent their body's immune system from rejecting and attacking the new body part.

So - called induced pluripotent stem (iPS) cells, which are derived from adult human tissue, have the added advantage of producing tissues and organs genetically matched to a recipient, avoiding the problem of immune system rejection.

«Signaling pathway helps protect healthy tissue from overly active immune responses.»

Lymphomas are cancers of immune cells that may have arisen from lymphatic tissue present in the breast tumors transplanted into the mice.

The immune system protects us from scores of invaders, but it can also turn against us when white blood cells called autoimmune T cells attack the body's own tissue.

In negative selection, the thymus presents proteins from foreign tissue to immune cells, in effect asking them, «Do you recognise this material?»

Rather than the body's immune system destroying its own tissue by mistake, researchers at the University of Bristol have discovered how cells convert from being aggressive to actually protecting against disease.

Because donated immune cells recognise the foreign tissue from the transplanted kidney, the thymus gets rid of the recipient's own T - cells that could otherwise attack the kidney.

To better understand how the different pieces of the immune system develop, immunologists Florent Ginhoux and Naomi McGovern at the Agency for Science, Technology and Research (A * STAR) in Singapore and their colleagues studied tissue from nearly 100 elective abortions performed between 14 and 22 weeks of gestation.

In obesity, the body's immune system can treat tissues as if they are suffering from a low - grade chronic infection.

Purpose: The development of the UNC Immuno - Oncology Patient Centered Translational Research (IMPACT) Biorepository involves the collection of tumor tissue and blood, as well as data (e.g., demographic, clinical, questionnaire) from patients attending Oncology Clinics at UNC Hospital and undergoing immune therapy through participation in a Merck IT trial at UNC.

HLAs help your infection - fighting system (immune system) tell the difference between body tissue and substances that are not from your own body.

Signals from pathogens, tissue factors, and other immune cells are involved in defining the immune phenotype of these cell types.

«Cytokines provide the intercellular communication links between the immune system and other tissues and organs... Thus, the study of cytokines has helped to propel immunology from the limited areas of immunological specificity to larger concerns of the cell biology, biochemical, molecular, and clinical aspects of host defense.»

If sufficient 1,25 - dihydroxyvitamin D is produced, it may exert paracrine effects on surrounding T lymphocytes, thereby regulating the tissue - specific immune responses.10 Some support for this hypothesis comes from recent experiments showing that mice fed diets high in vitamin D had significantly fewer clinical and pathological signs of EAE than mice fed a vitamin D — deficient diet.37 Central nervous system levels of 1,25 - dihydroxyvitamin D, but not blood levels, were higher in supplemented mice than in vitamin D — deficient mice and correlated inversely with disease severity.

To that end, Sharma gave an overview of MD Anderson's efforts to comprehensively characterize the activity of the immune cells in the patients they treat, and they've already analyzed over 42,000 tumor tissue samples, from both before and after treatment, looking for clues regarding how treatment outcomes relate to immune cell infiltration into tumors.