Not exact matches
There are actually a few
of those
drugs now: Cervarix, made by GSK, which targets strains 16 and 18; Gardasil, made by Merck, which preempts those two killers, plus strains 6 and 11; and Merck's Gardasil 9, which primes the body's
immune system to create protective antibodies against — you guessed it — nine
types of HPV.
So, Loncar took matters into his own hands and created a new
type of biotech index that focuses exclusively on the red - hot field
of cancer immunotherapy
drugs (treatments which use the body's
immune system as a conduit to fight cancer).
Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking
Drug use Severe mental health issue Epilepsy
Type 1 diabetes
Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because
of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto
immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women
(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking
Drug use Severe mental health issue Epilepsy
Type 1 diabetes
Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because
of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto
immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women
In his role as researcher, he developed a potential
drug to treat different
types of immune diseases and was able to accompany the molecule through the next stages?something most scientists at pharmaceutical companies are not able to do.
Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting
drugs and incorporating them into
immune cells to create a smart, targeted system to attack cancers
of specific
types.
Findings from a study in animals appear to demonstrate that temporarily blocking a
type of protein, called
type I interferon, can restore
immune function and speed up viral suppression during treatment with anti-viral
drugs for people with chronic infection
of the virus that causes AIDS.
The
drug's mechanism
of action was entirely new: Instead
of attacking cancer cells (like chemo), or indiscriminately revving up the
immune system (like IL - 2), ipilimumab blocked a single receptor on one
type of immune cell.
In an article published in the January issue
of Cancer Cell, the researchers describe how a new
type of immunotherapy
drug targeting the protein TIM - 3 works to stimulate the
immune system.
«Only three interventions — severely cutting the number
of calories consumed, restricting the amount
of methionine (a
type of amino acid found in meat and other proteins) in the diet and using the
drug rapamycin — have been shown to truly prolong the lifespans
of vertebrates, but eating less and not eating meat will not be welcomed by general population, while rapamycin has shown to suppress the human
immune system,» Liu said.
Groundbreaking findings, published online in the journal journal Cancer Cell, show that resistance to many
types of antibody
drugs can be overcome by preventing cancer cells from «hiding» from
immune cells.
Targeted
drugs made from engineered
immune proteins — called monoclonal antibodies — have revolutionised treatment for several
types of cancer in recent years.
It also may have helped several others by boosting the power
of a new
type of cancer
drug that uses a different mechanism to unleash an
immune attack on the tumor.
Immunity is key to long - term responses Knowing that the
immune system is capable
of recognizing distinctive features
of cancer cells and launching a T cell attack against those tumor antigens, and that checkpoint blockade removes a roadblock to that attack, it's logical that these
drugs should work against many tumor
types.
Although, Hedrick and Linden target different cell
types, innovations by both groups could encourage clinical tests
of drugs designed to switch on a patient's
immune cells by eradicating secondary lung malignancies.
However, the spikes present new binding sites for the human
immune response to infection and as such, may present promising new targets for the development
of different
types of drugs.
MD Anderson has more than 160 clinical trials open testing
drugs and cellular therapies that stimulate and support
immune attack against many different
types of cancer.
11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause
of Insulin Resistance Findings may have important potential for new
drug discoveries in fight against
Type 2 diabetes Researchers at the University
of California, San Diego (UCSD) School
of Medicine have discovered that inflammation provoked by
immune cells called macrop... More...
As with other
types of transplantation, the challenge with islet transplantation is to avoid rejection
of the donated organ and to balance that goal against side effects from the
drugs needed to control the
immune system.
Using the
drug aldesleukin (recombinant interleukin - 2), presently administered in high doses to combat kidney tumours and skin cancers, researchers at the University
of Cambridge hope to tailor its dosage to modulate the
immune response in
type 1 diabetes.
Candida normally lives in small, harmless numbers in your vagina, 4 but medications such as antibiotics can lower the probiotics (the good bacteria) in your vagina, causing yeast to spread.5 Corticosteroids, a
type of drug used to treat symptoms
of various diseases by lowering your
immune system, may also cause yeast to grow.
APOQUEL is not a steroid, antihistamine, or cyclosporine (a
type of drug that reduces
immune system activity).
Depending on the
type of allergy, treatment typically includes a combination
of anti-inflammatory
drugs such as corticosteroids, antihistamines and
immune - modifying medications (cyclosporine), medicated shampoos, topical sprays, parasite control and omega fatty acids.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell —
type of white blood cell Baso basophil —
type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection,
drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (
immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil —
type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake
of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver,
immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup
of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte —
type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part
of the C&S that determines antimicrobial selection Mono monocyte —
type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil —
type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)