Sentences with phrase «immunocompromised mice with»

Moreover, following transformation with H - Ras, these cells initiated tumor xenografts in immunocompromised mice with higher efficiency than their epithelial counterparts [5].
«If you infect immunocompromised mice with Pseudomonas,» Blackwell reports, «they are dead in about 48 hours.»

Not exact matches

Because mice with intact immune systems are resistant to S. stercoralis infection, the researchers began with an immunocompromised strain of mice, and then exposed some to a synthetic steroid called methylprednisolone (MPA) that is commonly used to treat asthma in humans.
To translate these findings into an in vivo setting, we performed a modification of the established in vivo spheroid - based angiogenesis assay35, by co-grafting HUVEC with WT or Tie2 - silenced BP in a gel matrix subcutaneously into immunocompromised mice.
Delaney et al. [4] who have shown that cord blood - derived CD34 + cells cultured in StemSpan ™ medium with cytokines, on plates coated with Notch ligand, are expanded ex vivo while still maintaining their ability to engraft into immunocompromised mice.
By culturing cells in a fed - batch system with StemSpan ™ medium containing cytokines and UM171, expanded cells were found to successfully engraft and repopulate immunocompromised mice, with no disadvantage when compared to unmanipulated cells.
Moreover, treatment with clinically approved mast - cell stabilizing compounds inhibited both mast cell activation and vascular leakage, in normal as well as immunocompromised mice.
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