Sentences with phrase «immunodeficiencies such»

He hopes that Cas9 - based therapies for T cell - related disorders, which include autoimmune diseases as well as immunodeficiencies such as «bubble boy disease,» will enter the clinic in the future.

Not exact matches

The second infection that's also been on the rise is Syphilis, particularly amongst populations that are at higher risk to contract Human Immunodeficiency Virus or HIV, such as young men who have sex with men or injection drug using adolescence.
«This is a universal molecule that can potentially treat not only autoimmune diseases, but other acute or chronic conditions such as allergy, chronic obstructive pulmonary disease, sepsis and immunodeficiency,» said Stefan G. Tullius, MD, PhD, BWH Chief of Transplant Surgery and Director of Transplantation Surgery Research, lead study author.
As such mutations rarely occur, these immunodeficiencies often go unrecognized or are detected too late for effective treatment.
Researchers for the past decade have focused on the T cell approach, based on studies showing that monkeys receiving such vaccines against simian immunodeficiency virus, related to HIV, lived longer or had lower viral levels than usual.
Notably, research groups might be able to apply the approach described in this study to develop treatments for other blood diseases such as β - thalassemia, severe combined immunodeficiency (SCID), chronic granulomatous disease, rare disorders like Wiskott - Aldrich syndrome and Fanconi anemia, and even HIV infection.
With this new understanding of the enzyme, called Inositol trisphosphate 3 - kinase B (ItpkB), scientists are closer to improving therapies for diseases such as bone marrow failure syndrome, anemia, leukemia, lymphoma and immunodeficiencies.
Since 1996, major changes in infectious diseases have occurred, such as the introduction of human immunodeficiency virus (HIV) / AIDS and West Nile virus into the United States, advances in HIV / AIDS treatment, changes in vaccine perceptions, and increased concern over drug - resistant pathogens.
Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, called the new work a «significant advance,» noting in a statement that it «opens the way to producing [monoclonal antibodies] that potentially could be used diagnostically or therapeutically» for the flu as well as other infectious diseases such as hepatitis C and the human immunodeficiency virus (HIV), which can lead to full - blown AIDS.
Other primate immunodeficiency viruses, such as SIV and HIV - 2, the rarer and less virulent human virus, do not need their host's cyclophilin A to replicate.
Researchers have discovered how the human immunodeficiency virus (HIV) first enters the body through mucosal surfaces such as the rectum, cervix and uterus.
This is in addition to the licensing of products such as GlaxoSmithKline's Strimvelis ex-vivo stem - cell therapy for treatment of severe combined immunodeficiency caused by adenosine deaminase deficiency (ADA - SCID) in 2016 (1)-- has led to an increase in demand for therapeutic vector manufacturing capabilities.
Other viruses, such as cytomegalovirus, herpes simplex virus types 1 and 2, varicella - zoster virus, human immunodeficiency virus, and chikungunya virus, have also been described to cause congenital malformations.16, 17
By supporting Directive 2010 / 63 / EU, LERU wishes to call attention to the fundamental importance of the use of animals in research and the vital role it plays in understanding and providing treatment for a range of debilitating and life threatening human diseases such as cancer, primary immunodeficiencies, neuro - degenerative diseases and heart failure.
This is of limited use in chronic conditions such as organ transplantation or HIV where the emphasis is on managing the condition to minimise immunodeficiency.
This condition may be present at birth, or it may be caused by certain infections (such as human immunodeficiency virus or HIV), or by certain cancer therapies, such as cancer - cell killing (cytotoxic) drugs, radiation, and bone marrow transplantation.
Secondary immunodeficiency (SID)-- acquired immunodeficiency as a result of disease or environmental factors, such as HIV, malnutrition, or medical treatment (e.g. chemotherapy).
The skimmed fat, however, can be used later as a cooking fat or added back to the diet as a nutrient, such as using marrow fat (majja) for vata disorders including immunodeficiency and weakness.
Zinc deficiency has been observed in acquired conditions, including malabsorption syndrome (McClain 1985), malnutrition (Keen 1990), cancer (Mocchegiani et al. 1994), alcoholism (Zarski et al. 1987), end - stage liver disease (Pescovitz et al. 1996), uremia (Mahajan et al. 1982) and chronic and acute infectious diseases such as human immunodeficiency virus (HIV) 3 type 1 (HIV - 1) infection (Ripa and Ripa 1995).
Most importantly it has been noted that the surgical instruments used during the FGM procedure are not sterilized, a fact that can cause serious and sometimes even fatal infections and diseases such as septicemia and HIV (human immunodeficiency virus)(Alston, et al, 2007 p. 547).
The most common causes of cat death in senior cats are kidney failure, cancer, and infectious disease such as FIV (feline immunodeficiency virus).
Cats with feline demodicosis can be coinfected with both species of Demodex mites, and, in one such case, a cat had feline immunodeficiency virus (FIV) infection.38 Clinical signs included alopecia, pruritus, crusting, scaling, erythema, and papules.
Screening for species related viruses such as Feline Leukemia and Feline Immunodeficiency Virus
Your veterinarian will also do blood tests to check your new kitten for viral infections, such as feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV).
Such vaccines are effective against Bordetella, feline leukemia virus, Chylamydophila felis, and feline immunodeficiency virus.
Senior animals and those that already have hypothyroidism, Cushing's disease or compromised immune systems, such as cats with feline leukemia or Feline Immunodeficiency Virus (FIV), are at an even higher risk of health complications due to the bacteria in their mouths when dental disease is present.
«Allowing cats outdoors increases their risk of being injured and exposed to infectious diseases such as feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV),» says Jane Brunt, DVM, veterinarian and owner of the Cat Hospitals at Towson and Eastern Shore, Md., and executive director of the CATalyst Council.
Many other feline eye diseases are attributable to viruses, bacteria and fungal organisms that specifically target cats — such as the feline immunodeficiency virus (FIV), the feline leukemia virus (FeLV), the feline infectious peritonitis virus (FIP), feline herpesvirus (FHP), toxoplasma (a parasitic organism) and cryptococcus (a yeast - like fungus commonly found in soil).
In this stage the cat may develop signs of immunodeficiency and secondary conditions, such as opportunistic infections, stomatitis, ocular inflammation, cancer, and respiratory tract infections.
I understand that some factors significantly increase surgical risk, including but not limited to, pregnancy, heat and diseases such and Feline Immunodeficiency Virus, Feline Leukemia and heartworms.
Also common are lung diseases associated with infection by feline immunodeficiency virus (FIV) and those caused by such parasites as heartworms and lungworms, although the prevalence of those parasitic infections depends to a great extent on geographical, climatic and seasonal factors.
Cats with symptoms for Cat Scratch Disease should be tested for diseases that may cause additional weakness in the immune system, such as FIV (Feline Immunodeficiency Virus) and Feline Leukemia, but if the feline patient is by all other means, healthy, then he should be able to make a full recovery following a course of antibiotic treatment.
Examples of lentiviruses — such as human immunodeficiency virus (HIV)-- were well known in primates, but the existence of a lentivirus that infects cats was not discovered until the mid-1980s.
Screening for viruses specific to felines, such as Feline Leukemia Virus and Feline Immunodeficiency Virus
Some vaccines, such as the FIV (Feline Immunodeficiency Virus) vaccine are usually not very efficient at stimulating immunity in the recipient.
In particular, people with immunodeficiency, such as AIDS or cancer, or who are undergoing chemotherapy, should use extreme care, especially when handling feces or after administering medications.
Underlying diseases can also be the cause such as feline leukemia virus (FeLV) feline immunodeficiency virus (FIV), feline infectious peritonitis (FIP) and diabetes mellitus.
While there can be specific causes of this chronic and frustrating inflammation such as viral infection with feline herpes virus (rhinotracheitis), calicivirus (FCV), feline leukemia virus and / or feline immunodeficiency virus, most of the time no specific causative agents can be found, placing the cause as ideopathic / immune mediated, which means that the cat's immune -LSB-...]
Your cat's veterinarian may suggest testing for occult infections such as feline immunodeficiency virus, feline leukemia virus and feline heartworms.
Depending on your cat's risk, we may also advise vaccinating him or her against other diseases, such as feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV).
Lastly, your veterinarian will try and rule out other causes such as feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV).
The veterinarian will also need to differentiate giardia from other illnesses that have similar symptoms such as inflammatory bowel disease, pancreatic insufficiency, bacterial overgrowth and immunodeficiency.
Uveitis is usually seen with other conditions such as a problem with the lymph nodes, disease caused by a parasite such as a protozoa, viruses such as feline herpesvirus, fungal infections, feline infectious peritonitis (FIP), feline immunodeficiency virus (FIV), feline leukemia virus (FeLV), toxoplasmosis (from a protozoa which is a one celled organism).
These include heartworm tests; feline leukemia / feline immunodeficiency virus test in cats; blood pressure evaluation; urine protein evaluation; cultures; imaging such as x-rays, ultrasound, and echocardiography; electrocardiography, and special ophthalmic evaluations, among others.
Primary skin infections are usually due to underlying immune system problems such as IgA deficiency or combined immunodeficiency that has been described in the breed.
Screening for viruses specific to felines, such as Feline Leukemia Virus (FeLV) and Feline Immunodeficiency Virus (FIV)
Similarly feline immunodeficiency virus, which is similar to HIV in people, only affects cats and can not infect people or other animals such as dogs.
In particular, people with immunodeficiency, such as AIDS or cancer, or who are undergoing chemotherapy, should use extreme care, especially when handling feces or litter or after administering medications.
Other heritable conditions that are related to loss of genetic diversity and inbreeding include cataract, various heart valve defects including pulmonic stenosis, hydrocephalus, cysteine urolithiasis, and hiatal hernias; immunologic disorders that include a propensity for severe demodectic mange indicative of immunodeficiency, allergies associated with atopic dermatitis and ear infections, and autoimmune diseases such as hypothyroidism; and cancers including glioblastoma, mast cell sarcoma and lymphoma [15, 16].
Dr. Levy also addressed other infectious diseases such as Feline Leukemia Virus (FeLV) and Feline Immunodeficiency Virus (FIV) by stating that, «A report published from the University of Florida on more than 1,800 feral cats showed only 4 % to be infected with feline leukemia virus or feline immunodeficiency virus, which is similar to that found in Immunodeficiency Virus (FIV) by stating that, «A report published from the University of Florida on more than 1,800 feral cats showed only 4 % to be infected with feline leukemia virus or feline immunodeficiency virus, which is similar to that found in immunodeficiency virus, which is similar to that found in pet cats.»
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