Sentences with phrase «immunodeficiency patients»

Not exact matches

These unusual symptoms led the cantonal hospital of Graubünden to refer the patient to the special clinic for immunodeficiency at the University Hospital Basel.

Prof. Mike Recher's research group at the Department of Biomedicine of the University of Basel and University Hospital Basel recently discovered a genetic immunodeficiency associated with serious, chronic autoimmune enteritis in an adult patient.

To study the pathogenesis of HIV - induced PNS disease, Jamie Dorsey, Research Technologist, and the research team led by Dr. Mankowski developed a simian immunodeficiency virus (SIV)- infected macaque model that closely reflects key peripheral nervous system (PNS) alterations seen in HIV patients with peripheral neuropathy.

Researchers have harnessed the CRISPR - Cas9 technology to correct mutations in the blood stem cells of patients with a rare immunodeficiency disorder; the engineered cells successfully engrafted in mice for up to five months.

Researchers have used radioimmunotherapy (RIT) to destroy remaining human immunodeficiency virus (HIV)- infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection.

A trial of a gene treatment for children with severe combined immunodeficiency, who have no functioning immune system, was called off after some of the patients developed leukaemia.

In a letter published in the cancer journal Annals of Oncology, researchers led by Professor Jean - Philippe Spano, head of the medical oncology department at Pitie - Salpetriere Hospital AP - HP in Paris, France, report that while treating an HIV - infected lung cancer patient with the cancer drug nivolumab, they observed a «drastic and persistent decrease» in the reservoirs of cells in the body where the human immunodeficiency virus (HIV) is able to hide away from attack by anti-retroviral therapy.

«This study found that patients with primary immunodeficiency disorders have a modest increase in overall cancer incidence.

The USIDNET registry gathers variables including clinical, laboratory and outcome data, which together provide a health survey of the relatively small number of patients affected by primary immunodeficiency disorders.

When Roswell Park Cancer Institute (RPCI) researchers evaluated the overall and site - specific incidence of cancer among patients registered in the United States Immune Deficiency Network (USIDNET), they found increased cancer incidence rates among patients with primary immunodeficiency diseases — and, in particular, a significant increase in lymphoma cases.

«Cancer diagnosed more often in patients with primary immunodeficiency diseases.»

Due to a congenital immunodeficiency and leukemia, respectively, stem cell transplants had to be performed on the two patients.

While antiretroviral drugs are generally successful in controlling the viral load in infected individuals, preventing the progression to acquired immunodeficiency syndrome (AIDS), some viruses remain hidden for years and can be reactivated if patients stop their treatment.

Discovery of a novel, advanced technique to identify the rare cells where human immunodeficiency virus (HIV) hides in patients taking antiretroviral therapy (ART).

Gene therapy's clearest success to date has been restoring the health of about 40 children with severe combined immunodeficiency (SCID), also known as «bubble boy» disease because patients can not fight off infections and are often isolated to protect them from germs.

Phase I Study of MK - 3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed / Refractory or Disseminated Malignant Neoplasm

Our physicians also provide outpatient evaluation and treatment of adults with allergic and immune disorders, particularly primary immunodeficiency, and consults for these patients who are admitted to Stanford University Medical Center.

A Phase I evaluation of the safety and immunogenicity of vaccination with recombinant gp160 in patients with early human immunodeficiency virus infection.

Patients with severe combined immunodeficiency (SCID) show unprecedented immune system recovery after receiving gene therapy developed at St. Jude.

St. Jude has played a key role in vector development, pioneering innovative vector designs for patients with hemophilia and the devastating immune disorder X-linked severe combined immunodeficiency (SCID).

Rubella persistence in epidermal keratinocytes and granuloma M2 macrophages in patients with primary immunodeficiencies.

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

«Patients who develop granulomatous lymphocytic interstitial lung disease (GLILD) as a complication of common variable immunodeficiency (CVID) often have poorer outcomes.

Biological and functional characterization of bone marrow - derived mesenchymal stromal cells from patients affected by primary immunodeficiency.

Immunodeficiency disorders result in partial or full impairment of the immune system, leaving the patient unable to effectively resolve infections or disease.

A prospective study on the natural history of patients with profound combined immunodeficiency (P - CID): an interim analysis.

LA JOLLA — Imagine a single drug that could prevent human immunodeficiency virus (HIV) infection, treat patients who have already contracted HIV, and even remove all the dormant copies of the virus...

Gene therapy is currently offered for a small number of immunodeficiency conditions, but with further research it is hoped that the therapy can be offered to more patients in the coming years.

The first gene therapy trials were carried out in 1990 treating a four - year old patient who suffered from severe combined immunodeficiency (SCID)(1).

She joined the Pillai lab as a post-doctoral research fellow in 2016 and continues to enjoy her work both treating patients with primary immunodeficiency in the clinic and studying the bridging gap between human primary immunodeficiency disorders and the development of autoimmune disease pathology in the lab.

Patient 2: NBAS c. 5741G > A p. (Arg1914His); c. 2032C > T p. (Gln678 *) in a 5 - year old boy with similar presenting features, bone fragility, mild developmental delay, abnormal liver function tests and immunodeficiency.

Howden and colleagues successfully combined these two steps in skin cells derived from an adult patient with retinal degeneration, and an infant patient with severe immunodeficiency.

«The new WITNESS FeLV - FIV Test Kit provides veterinary practices another dependable and affordable tool to support them in detecting leukemia virus antigen and immunodeficiency virus antibodies in their feline patients,» said J. Michael McFarland, DVM, DABVP and group director of Companion Animal Veterinary Operations for Zoetis.

Cats with symptoms for Cat Scratch Disease should be tested for diseases that may cause additional weakness in the immune system, such as FIV (Feline Immunodeficiency Virus) and Feline Leukemia, but if the feline patient is by all other means, healthy, then he should be able to make a full recovery following a course of antibiotic treatment.

This patient has no history of exposure to the bird manure, and she tested negative for the immunosuppressive diseases we see in cats (Feline Leukemia virus and Feline Immunodeficiency virus).

Dworkin, M.S., et al Bordetella bronchiseptica Infection in Human Immunodeficiency Virus — Infected Patients Clinical Infectious Diseases, 1999

We highly recommend this test be preformed on all feline patients at least once in their lives because Feline Leukemia and Feline Immunodeficiency Virus (Feline Aids) are viruses for which no cure exists.

Like our hope for zero AIDS patients, cat lovers everywhere hope to someday get to zero feline immunodeficiency virus (FIV) infections.

Markowitz JC, Kocsis JH, Fishman B, et al.Treatment of depressive symptoms in human immunodeficiency virus - positive patients.Arch Gen Psychiatry1998 May; 55:452 — 7OpenUrlCrossRefPubMedWeb of Science Question In HIV positive patients, is interpersonal psychotherapy or cognitive behavioural therapy effective in treating depressive symptoms compared with supportive psychotherapy with or without pharmacotherapy?

Treatment of Depressive Symptoms in Human Immunodeficiency Virus — Positive Patients.

Background This randomized clinical trial compared 16 - week interventions with interpersonal psychotherapy, cognitive behavioral therapy, supportive psychotherapy, and supportive psychotherapy with imipramine for human immunodeficiency virus (HIV)- positive patients with depressive symptoms.

This randomized clinical trial compared 16 - week interventions with interpersonal psychotherapy, cognitive behavioral therapy, supportive psychotherapy, and supportive psychotherapy with imipramine for human immunodeficiency virus (HIV)- positive patients with depressive symptoms.

Petrie, K.J., Pennebaker, J.W. et al. (2004) Effect of Written Emotional Expression on Immune Function in Patients With Human Immunodeficiency Virus Infection: A Randomized Trial.

It also addresses social isolation, a factor that has been linked to increased mortality and morbidity in some studies of patients with CAD.25 Furthermore, IPT was found to be superior to CBT in treating depression in patients with human immunodeficiency virus infection, 26 a group also dealing with comorbid physical and emotional problems.