Using the highly
immunodeficient NSG ™ mice [NOD.Cg - Prkdcscid Il2rgtm1Wjl / SzJ (005557)-RSB- as a host, they injected hu - PBMCs directly into the spleen along with HIV engineered to express luciferase (HIV - LucR).
Not exact matches
One of the most popular models is the
immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (
NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.
Humanized mouse models, where human tumor tissue is engrafted into
immunodeficient NOD SCID gamma (
NSG) mice, are frequently used in oncology and infectious disease studies to provide valuable translational insights.
NSG ™ variants are the most highly
immunodeficient mice and the models of choice for cancer xenograft modeling, stem cell...