Sentences with phrase «immunodeficient mice with»

In tests on human breast cancer cells and in special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cells.

Not exact matches

In this study, the Hiroshima University researchers developed an animal model using severely immunodeficient mice whose livers were partially populated with human cells, in order to reconstruct elements of the human immune system.

One of the most popular models is the immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.

To further validate our result in clinical samples, we obtained primary tumor from patients with advanced breast cancer and the tissue was passaged once in nonobese diabetic / severe combined immunodeficient mouse without in vitro culture.

Implementation of experimental procedures in cancerology and availability of 7 specialized laboratories of biosafety level BSL2 and BSL3, equipped with imaging (bioluminescence / fluorescence), surgery rooms with volatile anaesthesia, means of phenotypic characterization of immunodeficient mouse models, sensitization of murine tumours to radiotherapy and vectorized internal radiotherapy

To address the possibility that OspC is required for immune evasion, we inoculated severe combined immunodeficient (SCID) mice in parallel with WT, ospC mutant, and complemented clones (Table 4, which is published as supporting information on the PNAS web site).

Using the highly immunodeficient NSG ™ mice [NOD.Cg - Prkdcscid Il2rgtm1Wjl / SzJ (005557)-RSB- as a host, they injected hu - PBMCs directly into the spleen along with HIV engineered to express luciferase (HIV - LucR).