Sentences with phrase «immunogen used»

Paradoxically, it remains the case that even minimal mutation towards the J3 germ line V gene abolishes the ability to bind either immunogen used [26]; the reintroduction of the three germ line CDR2 residues renders the VHH incapable of binding Env.

A critical implication of this work for the field of HIV vaccine design is the observation that the most potent and broad individual anti-HIV VHH, J3, was elicited in response to the gp140 immunogens used.

Not exact matches

Using the findings from this study, the team has designed vaccine immunogens to selectively trigger the cooperating antibody - producing B cells to cooperate to make broadly neutralizing antibodies in a manner that mimics broadly neutralizing antibody development in natural HIV infection.

«Then the ultimate proof of utility of this discovery is to use it to design immunogens that can induce broadly neutralizing antibodies by vaccination.»

Finally, the gels can carry pathogens or immunogens, which means that they are not suitable for growing organoids to be used in the clinic.