Sentences with word «immunohistochemical»

Immunohistochemical is a term used in medicine and biology to describe a method that combines the use of antibodies and dyes to detect specific proteins or molecules in body tissues. Full definition
Based on the results of immunohistochemical analysis, the cells are TdT (+), CD56 (+), CD123 (+) and negative for myeloperoxidase (MPO), CD34, CD117, CD20, CD3 and EBV.
The ImmunoStar 5HT 6 receptor antibody was quality control tested using standard immunohistochemical methods.
To further confirm the alteration of DDX3 expression in cancer specimens, the expression profiles of DDX3 were examined in normal - tumor paired HCC samples by immunohistochemical staining analysis using specific anti-DDX3 antibody.
It indicates that immunohistochemical detection of the EGFR receptor improves clinical activity of necitumumab.
Research Paper Immunohistochemical Expression of Cyclin D1 in Invasive Ductal Carcinoma of Human Breast Mahmoud Assem, Eman Ahmed Youssef, Radwa Mohammed Rashad, Mona Abdel - Hamed Yahia Oncomedicine 2017; 2: 80 - 87.
HRP - RANbodies are, however, compatible with most multi-labeling immunohistochemical protocols where either a directly labeled primary or a primary / labeled secondary antibody are used to detect additional antigens.
Immunohistochemical examination of postmortem AD brains revealed that cytoplasmic accumulation of 8 - oxoG is evident in hippocampal CA1 and CA3 pyramidal neurons, and in neurons in the temporal cortex, where Aβ is also highly accumulated.
A few years later, Karl Deisseroth's lab developed CLARITY, which is a hydrogel - based method that also allows antibody penetration for immunohistochemical labeling in whole tissue (15).
Annotation of each different normal and cancer tissue is performed using fixed guidelines for classification of immunohistochemical results.
The ImmunoStar # 24505 5 - HT2C Receptor antiserum was quality control tested using standard immunohistochemical methods.
(F) Immunohistochemical assay of p - ERK in tumor samples of PTCL - NOS patients with or without KMT2D mutations.
Immunohistochemical imaging of female human amniotic stem cells incubated with nanoparticles demonstrated a significant increase in uptake compared to male cells.
What's more, the researchers found that simple immunohistochemical staining methods in tumor biopsy samples can show whether the tumor has high or low levels of H3K27me3 that could predict prognosis.
In order to test the sensitivity and specificity of spectral histopathology, the RUB team compared SHP with classical immunohistochemical methods, in which tumours are identified with the aid of fluorescent labels.
These structures were further examined by tissue - level and immunohistochemical tools, revealing ducts with «excessive layers» of epithelial cells, potentially pre-cancerous lesions that were «highly proliferative» compared to normal ducts, they add.
The facility utilizes various immunohistochemical techniques and has developed protocols for complex multiplex immunofluorescence on cryosections (fixed and unfixed) and paraffin embedded human and nonhuman tissue samples.
The presence of CB1 at presynaptic terminals was confirmed by immunohistochemical experiments with specific antibodies against CB1.
In their study «D - Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical method.
In RCC several immunohistochemical predictive biomarkers have been proposed for clear cell RCC including pS6 for temisorimus therapy and CAIX for high dose IL - 2.
While metastatic sites may have originated from the primary tumor, several studies have demonstrated a different immunohistochemical or mutation profile compared to the primary.
Previous immunohistochemical analysis of both fresh - frozen and / or paraffin embedded tissues showed that PD - L1 was variably expressed by primary and metastatic RCC tumor cells as well as TILs and although Thompson et al report slightly higher rates of PD - L1 expression in metastatic versus primary specimens, a thorough comparison in matched samples has not been made.
It is based on the experienced evaluation of positive immunohistochemical signals in the 76 normal cell types analyzed.
From selected areas, immunohistochemical reactions were performed using the following antibodies and dilutions: anti — glial fibrillary acidic protein (1:500), anti-neurofilament (1:2000), anti-CD3 (1:1000), anti-CD20 (1:1000), and anti-CD68 (1:1000).
Tsou et al. «Immunohistochemical Distribution of Cannabinoid CB1 Receptors in the Rat Central Nervous System», Neuroscience, 83 (2): 393 - 411, 1998.
In addition, I provide expertise in interpretation of histopathologic changes and immunohistochemical findings in animal models of GI and pancreatic diseases and in human GI and pancreatic diseases to collaborative scientists at Vanderbilt.
Reporter - nanobody fusions (RANbodies) as versatile, small, sensitive immunohistochemical reagents.
The team employs immunohistochemical, pharmacological, molecular biological, proteomic and tissue culture techniques in their research.
Jacquemier J, Moles JP, Penault - Llorca F, Adelaide J, Torrente M, Viens P, Birnbaum D, Theillet C. p53 immunohistochemical analysis in breast cancer with four monoclonal antibodies: comparison of staining and PCR - SSCP results.
These tumors can be difficult to differentiate, even with standard biopsy and special immunohistochemical stains are often required once a biopsy has been performed.
The vet will also be differentiating what they see from other possible diseases, such as systemic lupus erythematosus, and while doing that, may also conduct immunohistochemical or direct immunofluorescent testing.
Immunohistochemical diagnosis of chronic wasting disease in preclinically affected elk from a captive herd.
The study entitled «Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki - 67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues» was published in the scientific journal Oncotarget (ranked top 6 % of oncology journals).
For immunohistochemical localization of motor end - plates, serial cryosections (8 µm) were obtained from the external intercostal muscle of 1 affected Labrador Retriever, archived frozen muscle of a previously diagnosed Jack Russell Terrier with CMS due to AChR deficiency (neuromuscular disease control), and a normal dog (wild - type control).
TS, KM, AKK, LBV, and LJCvL designed the research; TS, PTR, JSJS, and SvV conducted the research; TS, JSJS, SvV, and JvK performed immunohistochemical analyses; TS, AKK, and LBV analyzed the data; TS, LBV, and LJCvL wrote the paper.
Immunohistochemical evaluation of IL - 31 receptor A localization in neuronal and cutaneous tissues of Beagle dogs
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