Sentences with phrase «immunologic checkpoint»
The potential for synergy with the combination of immunologic checkpoint blockade and radiotherapy has gained significant attention.
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Immunologic checkpoint blockade with anti — cytotoxic T - lymphocyte — associated antigen 4 (CTLA - 4) or anti — programmed death 1 (PD - 1) / programmed death ligand 1 (PD - L1) agents seems to have some degree of clinical efficacy in advanced mucosal melanoma, although data are limited to smaller retrospective series or subset analyses of prospective trials.
The potential for synergy between immunologic checkpoint blockade and radiotherapy is also being explored.