Sentences with phrase «immunoprecipitation approaches»
To this end, using knockout cells in combination with siRNA and immunoprecipitation approaches, our results revealed that Pen - 2 together with presenilin are sufficient... to form a functionally active enzyme to process Notch.
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Enter HITS - CLIP, a new approach that applies high throughput sequencing of RNAs isolated by crosslinking immunoprecipitation.
Furthermore, by chromatin immunoprecipitation and whole - genome scanning approaches, we show that the chromosome ends of senescent cells directly contribute to the DNA damage response, and that uncapped telomeres directly associate with many, but not all, DNA damage response proteins.