Sentences with phrase «immunoreactivities in»

Catecholaminergic neurons containing GABA - like and / or glutamic acid decarboxylase - like immunoreactivities in various brain regions of the rat

Ottersen OP, Storm - Mathisen J, Somogyi P (1988) Colocalization of glycine - like and GABA - like immunoreactivities in Golgi cell terminals in the rat cerebellum: a postembedding light and electron microscopic study Brain Res, 450 (1 - 2), 342 - 53 PubMed 2456823

Relationship of cannabinoid CB1 receptor and cholecystokinin immunoreactivity in monkey dorsolateral prefrontal cortex.

Note the absence of McSA1 - immunoreactivity in non-transgenic animals (m).

Bicker G, Schäfer S, Ottersen OP, Storm - Mathisen J (1988) Glutamate - like immunoreactivity in identified neuronal populations of insect nervous systems J Neurosci, 8 (6), 2108 - 22 PubMed 2898517

In our study, we observed strong Aβ - immunoreactivity in the amygdala at pre-plaque (intraneuronal) and post-plaque stages; changes which likely account for the fear conditioning deficits reported at both time points.

Note the absence of pab27576 immunoreactivity in amyloid plaques (a-c).

Doherty, J.M., Cooke, B.M., Frantz, K.J. (2013) Attenuated Fos immunoreactivity in prelimbic and infralimbic medial prefrontal cortex during heroin - seeking behavior in adolescent vs. adult male rats.

We assessed microgliosis by immunostaining for CD68 and found significantly elevated CD68 immunoreactivity in the frontal cortex, hippocampus, and thalamus of Grn − / − mice, as expected (Fig. 6A w - y).

Subsequent post hoc analysis revealed significantly lower CD68 immunoreactivity in exercised relative to sedentary Grn − / − mice (* p < 0.05).

A, Grn − / − mice had elevated CD68 immunoreactivity in the frontal cortex, hippocampus, and thalamus (ANOVA genotype effect, p < 0.0001).

Our quantitative assessment of doublecortin (DCX) immunoreactivity in the dentate gyrus showed a loss of DCX in aged animals (Supplemental Figure 1), consistent with a substantial decrease in the neurogenic capacity of the aged hippocampus.

Chronic rapamycin treatment tended to increase dentate gyrus DCX immunoreactivity in aged animals, but this effect was far from reaching statistical significance.

Bruner JM, Steiner JM, Williams DA, Van Alstine WG, Blevins W. High feline trypsin - like immunoreactivity in a cat with pancreatitis and hepatic lipidosis.

Serum feline trypsin - like immunoreactivity in cats with exocrine pancreatic insufficiency.

Recently, assays for measurement of pancreatic lipase immunoreactivity in dogs and cats (cPLI and fPLI, respectively) have been developed and validated.

Not exact matches

The most recent study report described in these same regions decreased tissue levels of 5 - HT and tryptophan hydroxylase, the synthesizing enzyme for serotonin, and no evidence of excessive serotonin degradation as assessed by levels of 5 - hydroxyindoleacetic acid (the main metabolite of serotonin) or ratios of 5 - hydroxyindoleacetic acid to serotonin.30 A recent article described a significant association between a decrease in medullary 5 - HT1A receptor immunoreactivity and specific SIDS risk factors, including tobacco smoking.40 These data confirm results from earlier studies in humans39, 41 and are also consistent with studies in piglets that revealed that postnatal exposure to nicotine decreases medullary 5 - HT1A receptor immunoreactivity.42 Animal studies have revealed that serotonergic neurons located in the medullary raphe and adjacent paragigantocellularis lateralis play important roles in many autonomic functions including the control of respiration, blood pressure, heart rate, thermoregulation, sleep and arousal, and upper airway patency.

MMP - 3 immunoreactivity was detected in cells within the lesion site, invading neutrophils, and blood vessel endothelial cells in the area outside of the initial injured area (the penumbra).

Some intragemmal fibers only show P2X3 immunoreactivity (arrows in E ′).

Regions of interest in the perikaryon of individual ganglion cells (as identified by P2X3 immunoreactivity) were outlined using ImageJ (RRID: nif -0000-30467).

GFP immunoreactivity was detected in a subset of geniculate ganglion neurons (169/682, 24.8 %; Fig. 2B, C), whereas the P2X3 signal was present in nearly all ganglion cells (664/682, 97.4 %; Fig. 2B, C).

(H) Cells expressing the rod photoreceptor marker XAP2 (rPR; red); BrdU - immunoreactivity (yellow) identifies mitotically active cells in the periphery of the same flank retina.

BrdU immunoreactivity was detected in all retinas tested (Figure 2H; Table S4).

Quantification of GFAP and Iba1 immunoreactivity revealed parallels in both mouse models in addition to distinct patterns of microglial activation.

Furthermore, in brains from APP transgenic mice conformation - specific antibodies have revealed the early appearance of intraneuronal fibrillar and oligomeric Aβ immunoreactivity, which declined as amyloid plaques appeared, and further became evident in the extracellular space [10].

McSA1 immunoreactivity remained limited to the intracellular compartment in heterozygote animals.

Notably, in DS brains intracellular Aβ immunoreactivity diminishes with increasing age and advanced AD pathology [18, 19].

Intense intraneuronal Aβ immunoreactivity is observed in McGill transgenic rats throughout the neocortex (a-c, g - i, o), hippocampus (a-f, n) and amygdala (j - l), as detected with the anti-Aβ McSA1 monoclonal antibody.

Corroborating our previous results with McSA1, we observed a differential pattern of immunoreactivity between MOAB - 2 and pab27576 in cells with detectable and reliable MOAB - 2 staining.

As seen in Figure 1, the antibody was highly specific for its target and showed strong immunoreactivity with the MEL624 PD - L1 + cells, but not the parental MEL624 cells.

When CCHa2 - R mutant larvae were fed, their IPCs showed increased Dilp2 immunoreactivity, which was much stronger than that observed in starved or fed control larvae (Fig 4C).

The uptake and degradation of fibrils was analysed by quantitative light - and electron - microscopic immunocytochemistry and immunoreactivity was detectable in 86 + / -3 % cells within 6 h of culture.

Effects of neonatal treatment with valproic acid on vasopressin immunoreactivity and olfactory behaviour in mice.

CCHa2 immunoreactivity was also detected in endocrine cells in the gut as previously reported [20](Fig 1F).

The reduction in CD68 immunoreactivity between sedentary and exercised Grn − / − mice is consistent with the general anti-inflammatory effects of exercise, including those found in other mouse models of neurodegenerative disease (Gleeson et al., 2011; Stranahan et al., 2012).

For stereology, every fourth section through the midbrain was stained for glial fibrillary acidic protein (GFAP) and / or tyrosine hydroxylase (TH) immunoreactivity using a free - floating procedure in which all steps were performed on a rotating shaker (∼ 250 rpm).

B: Double - labeling of ZENK and the retrograde tracer BDA in sagittal brain sections at the level of Cluster N proves the correct placement of tracer into Cluster N: arrows point to examples of neurons displaying ZENK - immunoreactivity (shown in magenta) in the nucleus together with BDA (shown in green) in the somata.

Dietary lectins tend to show immunoreactivity to connective tissues in autoimmune arthritis.

These limitations have led to the development of assays for enzymes or markers considered pancreatic in origin such as trypsin - like immunoreactivity (TLI), trypsinogen activation peptide (TAP), and pancreatic lipase immunoreactivity (PLI).

Serum trypsin - like immunoreactivity, amylase and lipase in the diagnosis of feline acute pancreatitis.

Serum trypsin - like immunoreactivity (TLI) is an assay that mainly measures trypsinogen in serum, but will also detect trypsin and some trypsin molecules bound to proteinase inhibitors.

Serum feline trypsin - like immunoreactivity concentrations in cats with normal serum cobalamin concentrations and cats with low serum cobalamin concentrations.

Levels of total alpha - macroglobulin and trypsin - like immunoreactivity are poor indicators of clinical severity in spontaneous canine acute pancreatitis.

Trypsin - like immunoreactivity (TLI) tests are the most specific of the lab tests, but changes are not always present in affected cats.

In 2005, IDEXX Reference Laboratories developed a blood test called Spec cPL (canine pancreas - specific lipase), based on the cPLI (canine pancreatic lipase immunoreactivity) test developed at Texas A&M University.

Interpretation of tyrosin - like immunoreactivity (TLI) values in fasting dogs.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)

For this reason, a vet may fail to consider EPI as a possible diagnosis in other breeds and not pursue EPI testing: a trypsin - like immunoreactivity (TLI) blood test.