The BCR - ABL inhibitor ponatinib inhibits platelet
immunoreceptor tyrosine - based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear.
The sequence, called an ITAM (
immunoreceptor tyrosine - based activation motif), encodes a piece of protein that can by itself signal immune system cells to multiply and go to work.
Not exact matches
Larry Samelson provides the first demonstration that the TCR is coupled to
tyrosine kinase pathways, now known to be true for all
immunoreceptors.