Sentences with word «immunosuppressant»

But heavy use of immunosuppressant drugs weakened her and she succumbed to cancer in April at the age of 49, the BBC's Hugh Schofield in Paris...

Also according to the company's studies, there are risk factors for MS patients that make them more vulnerable to developing PML: Previous use of immunosuppressant drugs, use of Tysabri for two years, or contraction of the JC virus are what can up a patient's risk.

This may mean that they can be used as immunosuppressants and as an anti-inflammatory (22).

The patient takes immunosuppressant drugs that not only protect the new organ from future attacks, but also helps keep lupus in remission overall.

Your veterinarian will prescribe a treatment plan that is aimed at attempting to counteract the body's immune system response by suppressing the immune system with immunosuppressant medications.

(Volunteers in these trials nonetheless received immunosuppressants for 12 weeks as a precaution.)

More frequent causes of treatment failure include poor pyoderma control, premature discontinuation of therapy, unsuccessful control of underlying conditions, and the use of immunosuppressants such as glucocorticoids.

In the past, the virus usually only developed into brain disease in individuals with suppressed immune systems, such as AIDS patients and organ transplant recipients on immunosuppressant medications.

Patients with Crohn's disease, psoriasis, rheumatoid arthritis, B cell lymphoma and chronic lymphocytic leukemia have also developed the devastating brain disease after immunosuppressant therapy with natalizumab and other drugs.

Some patients were receiving immunosuppressant medications.

Treatment involves the use of corticosteroids in combination with other immunosuppressant drugs such as azathiaprine, cyclosporine or leflunomide which are usually continued for several months after remission has been achieved.

Sick cats are more likely to suffer from localized infections of demodectic mange; cats who suffer from immunosuppressant diseases are most likely to develop generalized symptoms of demodectic mange.

Almost all of the patients with melanoma were white and they were more likely to be taking the common immunosuppressants cyclosporine or sirolimus than those without melanoma.

It is not yet clear whether they do in fact evade attack, because the monkeys were given immunosuppressant drugs.

The study, believed to be the first to look at CKD in children who have received lung transplants, also found that those children with high levels of tacrolimus, a powerful immunosuppressant given to fight organ rejection, circulating in the blood and those who experience at least one episode of acute kidney injury during their recovery also appear to be at greater risk for CKD.

Treatment involves topical treatments (cortisone creams, coal tar or anthralin containing creams, moisturizers, vitamin D and vitamin A), novel systemic immunosuppressant drugs (e.g. etanercept, infliximab, etc.) and phototherapy.

In an effort to control their symptoms, many children are prescribed powerful medications like immunosuppressants or topical steroids.

Rapamycin, an antibiotic and immunosuppressant approved for use about 15 years ago, has drawn extensive interest for its apparent ability — at least in laboratory animal tests — to emulate the ability of dietary restriction in helping animals to live both longer and healthier.

But new immunosuppressant drug regimens and a wealth of new genetically engineered pig varieties have changed the equation, says transplant immunologist David Cooper of the University of Alabama in Birmingham.

The research was originally undertaken to see if Everolimus is gentler on the kidneys than Tacrolimus, the most commonly prescribed immunosuppressant drug.

Titus says that the way the cells were developed means recipients don't need immunosuppressants.

«This new approach to delivering immunosuppressant therapy suggests that local delivery of the drug to the grafted tissue has benefits in reducing toxicity, as well as markedly improving therapeutic outcomes, and may lead to a paradigm shift in clinical immunosuppressive therapy in transplant surgery,» said Jeff Karp, PhD, Division of Biomedical Engineering, BWH Department of Medicine, co-corresponding study author.

(Neoral, Sandimmune) An immunosuppressant, this drug that lowers the body's immune response.

Inhibitory control Other strategies being pursued to prevent the formation of inhibitors of clotting - factor therapy include immunosuppressants and drugs that deplete specific immune cells.

Of the eight recipients, five were completely off immunosuppressants, with no sign of GVHD, within a year, and their kidneys have continued to function well for an additional 18 months.

Following a tissue graft transplant — such as that of the face, hand, arm or leg — it is standard for doctors to immediately give transplant recipients immunosuppressant drugs to prevent their body's immune system from rejecting and attacking the new body part.

And there is a big roadblock to testing drugs designed to induce tolerance: It is hard to know if they work unless immunosuppressant drugs are withdrawn, and that would risk rejection of the transplant.

In fact, in the 18 ASD cases observed in offspring of lupus mothers with public drug coverage, none of the children were exposed to antimalarials, antidepressants, or immunosuppressants during pregnancy.

In 1992 Starzl observed something that convinced him to rethink the way immunosuppressants are used.

Warshaw said patients who get immunosuppressants can respond very differently to regular cancer treatments.

The project aims to develop an insulin - injection - free treatment, without immunosuppressants, to benefit diabetes patients who require insulin.

After running thousands of drugs through the supercomputer, they found that methyldopa not only blocked DQ8, but it didn't harm the immune function of other cells like many immunosuppressant drugs do.

Doctors treat skin inflammation with topical steroids, or in more severe cases, administer immunosuppressants, similar to those used to treat other autoimmune diseases.

ViaCyte's PEC - Encap ™ (also known as VC - 01) product candidate delivers the same cell therapy as the PEC - Direct product candidate but in a delivery device designed to protect the cells from the patient's immune system, and therefore will not require immunosuppressant drugs commonly used for organ and tissue transplants.

Anti-TNFs and immunosuppressants provide most patients with relief and are useful in effective long - term treatment options as they reduce inflammation.

It is still unknown how immunosuppressant therapies may cause these mutations in JCV, the researchers said.

The drugs used to suppress the immune system are relatively well understood but have significant side effects and at the moment gving immunosuppressants to a person without illness is very different from using the drugs to maintain transplants which save lives.

Treatments involving immunosuppressant drugs increase the risk of severe infections and cancer when taken for long periods of time.

For example, exposure to toxic metals such as mercury can contribute to malnutrition and, conversely, malnutrition may also increase susceptibility to mercury toxicity.39, 40 Mercury is also a potent immunosuppressant, which has implications in low - resource settings where children already face numerous other health challenges and environmental pollutants.41

«I have observed that a small number of my own IBD patients drastically improved on the SCD and achieved complete long - term mucosal healing, or were able to reduce or discontinue immunosuppressants for several years.

In most cases, corticosteroid and immunosuppressant administration can block the antigen / antibody reaction and thus prevent further breakdown of red cells.

In order to prevent rejection, Milo receives immunosuppressants twice a day.

Treatment is mainly aimed at decreasing the inflammation and autoimmune activity, which is why western treatment centers around ant - inflammatory and immunosuppressive medications such as steroids, and sometimes includes additional immunosuppressants such as azathioprine, cyclophosphamide, or cyclosporine.

We treat this disease with supportive care, antibiotics, low - protein diets and sometimes immunosuppressants.

If the blepharitis is idiopathic, the symptoms may be controlled with topical medications; in some cases oral immunosuppressants may be necessary.

They discuss the benefits and risks of immunosuppressants such as natalizumab, fingolimod and others as well as new treatments under investigation.

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often - fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.

Allergic disorders can be controlled with oral broad - spectrum antibiotics and corticosteroids or other immunosuppressant medications along with avoidance of the allergen.