Sentences with phrase «immunosuppression which»

Not exact matches

While difficult to achieve, immune tolerance — in which a transplanted organ is accepted without long - term immunosuppression — can be induced in some patients.

Understanding which cytokines are best for monitoring inflammation and immunosuppression, and knowing which are secreted by different immune cell types at each stage of maturation and activation, will provide essential insights into disease treatment options.

This exhaustion may lead to immunosuppression, which can also have fatal consequences due to increased susceptibility to secondary, opportunistic infections.

BIOCAPAN, which stands for BIOactive implantable Capsule for PANcreatic islet immunosuppression free therapy, is a four - year project funded by the European Union through a research and innovation program.

PD - 1 is a receptor present on activated T cells, which mediates immunosuppression primarily in peripheral tissues, where PD - 1 ligands, PD - L1 and PD - L2 share an immunosuppressive activity and may be produced by either tumor cells or stromal / tumor - infiltrating immune cells.

iTeos is currently reviewing the full data set and plans to continue the development of EOS200271 in oncology indications, which have demonstrated an important role of IDO1 in immunosuppression.

And this comes back to the application we were talking about before that has relevance, I think for your audience, for athletes, which is if you're exercising too much and you're causing immunosuppression in the gut, you risk having a bacterial overgrowth in the gut, or a fungal overgrowth, and this could be one tool toward helping to reverse that, or treat that, or what have you.

This results in cancer cells secreting large amounts of the fermentation product lactic acid into their extracellular microenvironment, lowering the extracellular pH to 6 - 6.5, contributing to acidosis, initiation of angiogenesis and providing a metabolic fuel for cancer cells, which also induces immunosuppression.

FeLV can cause cancer by directly promoting transformation of normal cells into cancerous cells, and by causing significant immunosuppression, which makes a cat more vulnerable to both infections and cancer.

Specifically, the ACE Study model relies strongly on the idea that adverse childhood experiences create a burden of psychological stress that changes behavior, cognitions, emotions, and physical functions in ways that promote subsequent health problems and illness.22 Among the hypothesized pathways, adverse childhood experiences lead to depression and posttraumatic stress disorder, which in turn can lead to substance abuse, sleep disorders, inactivity, immunosuppression, inflammatory responses, and inconsistent health care use, possibly leading to other medical conditions later in life.23, 24 Therefore, childhood behavioral and emotional symptoms very likely represent a crucial mediator linking adverse childhood experiences and the longer term health - related problems found in the ACE substudies.