Sentences with phrase «immunosuppressive drugs»

Immunosuppressive drugs are medications that weaken the immune system, which is the body's defense against germs and diseases. These drugs are often used in medical treatments to prevent the immune system from attacking transplanted organs or to treat certain autoimmune diseases. Full definition
Dogs with acquired megaesophagus often benefit from administration of immunosuppressive drugs such as steroids, although these medications can have some serious side effects that should be discussed with the dog's veterinarian before treatment begins.
Islet recipients currently must take immunosuppressive drugs for the rest of their lives to prevent their immune systems from rejecting the transplanted cells.
By receiving transplants of bone marrow cells along with the new kidney, four of five transplant patients with end - stage renal disease were able to stop taking immunosuppressive drugs within about one year after surgery.
«Furthermore, the recipient animals only needed treatment with immunosuppressive drugs for five days after transplantation, rather than the ongoing immunosuppression that would be needed for unmatched organs.»
Many cats need long - term corticosteroids or other immunosuppressive drugs such as cyclosporin.
As a result, most transplant patients must stay on immunosuppressive drugs for life so that their bodies don't reject the new organ.
For decades, transplant experts have observed that liver transplant recipients often need less anti-rejection medication, known as immunosuppressive drugs, than recipients of other solid organs.
Cell transplantation as a treatment for diabetes is still essentially experimental, uses cells from cadavers, requires the use of powerful immunosuppressive drugs, and has been available to only a very small number of patients.
Other immunosuppressive drugs such as cyclosporin which allows for the use of less steroid but is a powerful drug that absolutely affects the patient's immune system.
«This treatment is a new form of cell transplantation that utilizes the patient's own cells, so it does not require immunosuppressive drugs and, thus, avoids the side effects of those drugs,» says Scott Nyberg, M.D., Ph.D., a liver transplant surgeon at Mayo Clinic.
New immunosuppressive drugs also have made it possible to transplant bone marrow or peripheral stem cells from a donor less closely matched to the host.
The main predisposing risk factors for fungal infection include alterations in immunity associated with broad - spectrum antibiotic therapy, poor and sugary diet, nutrient deficiencies, heightened toxic exposure, stress, underlying malignancy, HIV infection, organ transplantation, chemotherapy and other immunosuppressive drug therapy.
The treatment for IMHA includes immunosuppressive drugs like prednisone and azathioprine (Imuran).
If none of these medications successfully controls the symptoms of IBD, more potent immunosuppressive drugs, such as chlorambucil or azathioprine, may be necessary.
Immunosuppressive drugs like prednisone and other steroids are prescribed specifically for EGC, and may be given for weeks until response is seen.
Patients receiving standard immunosuppressive drugs after transplant, as opposed to high - dose cyclophosphamide, have slower recovery of regulatory T - cells in their blood, adds Kanakry.
It spends more than a billion dollars a year on immunosuppressive drugs alone, which prevent the recipient's immune system from rejecting the transplanted organ.
Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.
Until the patient received her final immunosuppressive drug, that is.
The JDF Center for Islet Cell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantation.
Soon, Luciana was downing immunosuppressive drugs that caused her cheeks to bloat, her hair to thin, and her menses to stop.
After the transplant, the monkeys were given immunosuppressive drugs to prevent the new cells from being rejected and observed for up to two years.
In heart, liver and kidney transplants, knocking down memory T cells with immunosuppressive drugs helps to ensure that the immune system recognizes a new organ as the body's own.
From an entire organ to a dose of embryonic stem cells, if the tissue's DNA came from anyone else, the transplant would be rejected without the aid of harsh immunosuppressive drugs.
«Most immunosuppressive drugs were adopted for use in lung transplants based on their results in other solid organ transplants, without an appreciation that the lung is different,» Kreisel said.
The immune rejection that complicates organ transplants, and normally requires long - term immunosuppressive drug therapy, may also be treatable with CAAR T cell technology.
When left untreated, PV leads to extensive skin blistering and is almost always fatal, but in recent decades the condition has been treatable with broadly immunosuppressive drugs such as prednisone, mycophenolate mofetil, and rituximab.
Following transplant surgery, Strober's team first give patients ordinary immunosuppressive drugs, such as cyclosporine.
And iPS cells may have a particular advantage: Taking a person's own skin cells, say, making them pluripotent, and then using those cells to grow whatever kind of tissue is needed could eliminate the use of debilitating immunosuppressive drugs, which are required when transplanting cells or tissue from a donor.
There is no known cure for Sjögren's syndrome, but symptoms can be managed with both over-the-counter products like artificial tears and sugar - free lozenges and prescription immunosuppressive drugs.
Cyclosporine is a unique immunosuppressive drug that interferes with T helper cell activity.
Treatment: Topical immunosuppressive drugs are usually effective in controlling the disease, so long as they are applied consistently and as directed.
Anti-inflammatory or immunosuppressive drugs treat autoimmune causes.
In order to treat this, immunosuppressive drugs work to slow down the immune system response.
Answer: Erythema multiforme is so rare, you may want to consider seeing a veterinarian that specializes in dermatology - they will know what immunosuppressive drug beyond prednisone and cyclosporine that is working well.
If the dog's condition does not improve, stronger immunosuppressive drugs, including chemotherapeutic agents, can be added to the mix.
Additional immunosuppressive drugs may also be needed, especially in more severe cases.
The Western approach utilizes immunosuppressive drugs to keep the immune system from being over-reactive.
If you suffered serious complications caused by the rheumatoid arthritis immunosuppressive drug Actemra, you may be able to file a lawsuit to secure the compensation you need.
Organ transplantation is a challenge, requiring immunosuppressive drugs and careful matching of donor and recipient for human leukocyte antigen markers, receptors on immune cells that recognize foreign proteins.
To prevent rejection, kidney transplant recipients typically take immunosuppressive drugs every day.
And anyone who's had a transplant now has a functional kidney but would have to be on immunosuppressive drugs for life which basically means he is then prone to infections and cancers.
When T cell function declines, such as with increasing age or during use of immunosuppressive drugs, viral clearance is delayed.
Couch remembers the time, before the ACA, when a new immunosuppressive drug that wasn't covered by her policy became available.
If the aforementioned therapies do not produce results, it may be necessary to use more potent immunosuppressive drugs.
Research is ongoing to find other immunosuppressive drugs that may slow down the progress of the disease.
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