Sentences with phrase «immunosuppressive factors»

Tumors can suppress CD4 + T cell activity and CTL tumor lysis directly through secretion of immunosuppressive factors including TGF - β1 but also PGE - 2, and IL - 10.

Not exact matches

They show that it is a substrate for calcineurin, the phosphatase target of the immunosuppressive drugs cyclosporin A and FK506, and that it exists in activated cells as a complex with the transcription factor AP - 1 (Fos - Jun).

Higher rates of disease occur in children aged less than one year, children aged 1 — 4 years and adolescents 15 — 19 years of age.1 Reported risk factors for IMD include household crowding, chronic underlying illness, active and passive smoking, some immunosuppressive illnesses and anatomical or functional asplenia.2