Sentences with phrase «immunosuppressive tumor environment»
Not exact matches
«This trial showed that there is a need to target additional antigens in glioblastoma, as well as overcome the immunosuppressive environment that the CAR T cells encountered in the tumor,» Maus said.
https://www.sciencedaily.com/
To avoid being targeted by their hosts» immune systems, tumors maintain an immunosuppressive environment by manipulating the characteristics of the immune and vascular system.
While previous research had shown some effectiveness of this molecule in a mouse model of ovarian cancer, that benefit was limited by the immunosuppressive environment within tumors, particularly the presence of regulatory T cells (Tregs).