Scientists at the UNC School of Medicine and NC State have created an injectable gel - like scaffold that can hold combination chemo -
immunotherapeutic drugs and deliver them locally to tumours in a sequential manner.
«Since the advent of cancer immunotherapy, people have tried to apply
immunotherapeutic drugs to mesothelioma with limited success.
One class of
immunotherapeutic drugs is known as «checkpoint» inhibitors, as they target checkpoints in immune system regulation to allow the body's natural defenses, such as white blood cells, to more effectively target the cancer.
«Targeting FAS - ligand could be a good adjunct therapy to boost the effects of
immunotherapeutic drugs.»