Sentences with word «immunotherapeutics»

Correction: June 29, 2017, 4:00 P.M.: An earlier version of this article mistakenly named Innate Immunotherapeutics as Innate Pharma.

Career Goals: Developing of novel immunotherapeutic strategies for the treatment of chronic allergic inflammation and airway remodeling.

Peter P. Lee, M.D., the Billy and Audrey L. Wilder Professor in Cancer Immunotherapeutics at City of Hope, has for two decades been interested in treating cancer by stimulating or enhancing a person's own immune system.

BACKGROUND: In a phase 2a clinical trial of AN1792 (Study 201), a potential immunotherapeutic agent for use in Alzheimer's disease (AD), approximately 6 % of the treated AD patients (18/300) developed meningoencephalitis (ME).

Home / NEWS & MEDIA / Zoetis Presents New Data on Canine Atopic Dermatitis Immunotherapeutic *, a Therapeutic Antibody for Dogs with Atopic Dermatitis, at the 8th World Congress of Veterinary Dermatology

Known as immunotherapeutic vaccines, they enlist a neutered version of viruses to infect healthy T cells and genetically modify them to target the disease.

A study led by scientists at The Wistar Institute describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer specific protein.

«Targeting FAS - ligand could be a good adjunct therapy to boost the effects of immunotherapeutic drugs.»

Democrats, including Congresswoman Louise Slaughter, have raised questions about whether Collins helped his friends and colleagues buy shares of Australian pharmaceutical company Innate Immunotherapeutics at a discount, while using his influence to make the company more valuable.

A Phase 1 study completed in 2013 led by Wolchok, who leads the Ludwig Collaborative Laboratory at MSK and is also the Chief of the Melanoma and Immunotherapeutics Service at MSK, found that the same concurrent combination of therapies generated notably positive responses in previously treated patients.

My research is focused on elucidating the molecular mechanisms underlying a protective anti-tumor immune response with the goal of identifying novel immunotherapeutic targets.

«A lot of studies are underpowered and not controlled appropriately,» says Vincent Brichard, who heads GSK's antigen - specific cancer immunotherapeutics program.

Dr. Wolchok has been at the forefront of cancer immunotherapy, as an active clinician scientist exploring innovative immunotherapeutic strategies in laboratory models and as a principal investigator in numerous pivotal clinical trials.

Nonetheless, the first cellular immunotherapeutic product on the market has generated $ 228M revenue in 2011.

This two - day scientific symposium will explore cutting - edge findings in basic science, translational research, and clinical studies to improve immunotherapeutic approaches.

Rep. Chris Collins quietly resigned last week from the board of Innate Immunotherapeutics amid major corporate changes and a fresh round of controversy about the Clarence Republican's investment in the Australian biotech firm and legislation he has introduced that could conceivably help it.

Although cancer immunotherapy is changing the paradigm of how cancer is treated, there is an urgent need to develop predictive biomarkers to identify patients who are most likely to benefit from various immunotherapeutic strategies.

Entolimod, the lead drug candidate of Cleveland BioLabs Inc., of Buffalo, N.Y., activates toll - like receptor 5 (TLR5) and has been shown to have immunotherapeutic effects in preclinical cancer models.

Therefore infusing similar cells into humans could improve on immunotherapeutic methods for controlling CMV infection,» said first author Michael Quinn MD / PhD student in the Department of Microbiology and Immunology at Thomas Jefferson University.

The bill could benefit Innate Immunotherapeutics if it ever seeks a clinical trial in the United States.

About Collins» Innate Immunotherapeutics investment — which has led to an Office of Congressional Ethics investigation — Cole said: «He's focused on himself and self - promotion, building his own wealth, bragging to people that he's making millionaires in Buffalo when people in his own district never see him.»

Collins, who has denied any wrongdoing, was the largest shareholder of Australia's Innate Immunotherapeutics Limited and sat on the company's board of directors.

Particularly, he said allegations that Collins» dealings with Australian pharmaceutical company Innate Immunotherapeutics potentially broke House rules and federal laws are resonating with voters.

«Congressman Collins» relationship with Innate Immunotherapeutics dates back more than 15 years.

This still experimental immunotherapeutic strategy paves the way for new treatments against lymphoma.

But questions remain about whether Price, whose shares in Innate Immunotherapeutics boomed shortly after his purchase last fall, secured a deal that was not available to the general public.

Several checkpoint inhibitors have been shown to be effective immunotherapeutic agents.

«Since the advent of cancer immunotherapy, people have tried to apply immunotherapeutic drugs to mesothelioma with limited success.

We further report evidence for an interaction between oncogenic mutations and host response to melanoma, suggesting that patient stratification will improve immunotherapeutic outcomes.

«Future neoantigen vaccine trials will recruit more patients with advanced disease to test the efficacy of the vaccine, take advantage of improved methods for predicting antigen presentation to boost the number of effective neoantigens and test for synergy with checkpoint blockade and other immunotherapeutics,» the scientists said.

The Vaccine and Immunotherapeutic Research Laboratory is a mixed - use space consisting of a 1,200 - square - foot wet lab and a 400 - square - foot computer / bioinformatics suite.

Our findings show how the tumor microenvironment drives the acquisition of CD39 as an immune regulatory molecule on CD8 + T cells, with implications for defining a biomarker of T cell dysfunction and a target for immunotherapeutic intervention.

The collaboration is part of the company's overall plans to find new partnerships «focused on technology development and refinement for applications critical to regenerative medicine and immunotherapeutic areas.»

Unum Therapeutics Cellular immunotherapeutic, clinical stage startup from Cambridge (MA), founded last year.

Progress in the active immunotherapeutic approach to Alzheimer's disease: clinical investigations into AN1792 - associated meningoencephalitis.

We're driving discovery research in immuno - oncology which is leading to new and exciting immunotherapeutic possibilities.

Bilthoven, April 21, 2016 - An international multi-disciplinary consortium of 11 partners, in which 5 leading academic institutes, 4 cutting - edge biotech companies and 2 excellent service providers will join forces to advance the treatment of cancer using an innovative immunotherapeutic nanomedicin, has received an $ 8.3 million Horizon 2020 grant (grant agreement No 686089).

Immunotherapeutic trials using this treatment approach in AD patients are in progress.

The patch could also be used to deliver immunotherapeutic drugs directly to the skin tumor, through microscopic needles that are conical - shaped, a therapy that appears to be effective in mice, Ye says.

Restoring the balance: immunotherapeutic combinations for autoimmune disease.

hen tiny Australian biotech firm Innate Immunotherapeutics needed to raise money last summer, it didn't issue stock on the open market.

I am interested in understanding how dengue virus and zika virus - specific T - cell responses can mediate protective immunity or disease pathogenesis, and in defining new protective T - cell epitopes for immunotherapeutic reagents or novel vaccine development.

Australian biotech firm Innate Immunotherapeutics sold nearly $ 1 million in discounted shares to two US congressmen, including Representative Tom Price.

Elucidating at the molecular level how these TLRs are precisely directed into the compartments that define their downstream signaling will enable us to better understand their biology and help modulate their activity during immunotherapeutic strategies.

Young Kim, M.D., Ph.D., Associate Professor of Otolaryngology and co-leader of the Translational Research and Interventional Oncology Research Program, is a clinician - scientist focused on the development of immunotherapeutic modalities for solid tumors.

CALM study: secondary endpoints of a phase II study of a novel oncolytic immunotherapeutic agent, coxsackievirus A21, delivered intratumorally in patients with advanced malignant melanoma.