Sentences with phrase «immunotherapy strategies for»
She translates the most promising immunotherapy strategies for breast cancer to the clinic, and is now extending these strategies to ovarian cancer.
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The researchers are developing a potential new immunotherapy strategy for melanoma based on their insights into Autoimmune Polyendocrinopathy Type 1, a rare, inherited disorder in which T - cells attack healthy cells and tissues.
Not exact matches
«Discovery opens door to new strategy for cancer immunotherapy.»
In addition to formulating diagnostic strategies for cancer immunotherapy agents, her team is focused on developing a deep understanding of tumor immune biology as well as mechanisms associated with immune response and immune escape in cancer patients, with the intent of generating rational strategies for the creation of combination therapies.
«Our research sheds light on the mechanism of this impairment, pointing us in the direction of new strategies for improving the response to immunotherapy.»
Combining their strategy with an existing immunotherapy treatment that works by releasing the «brakes» on immune cells, they found they could shrink melanoma tumors, and prolong survival in preclinical models for melanoma.
Traditional treatments are invasive and can impair the quality of life of patients, underscoring the need for alternative therapeutic strategies, including immunotherapy.
Immunotherapy is a promising strategy for the treatment of Alzheimer's that uses antibodies to stimulate the immune system to remove pieces of a protein called amyloid beta which accumulates in the brain (in deposits known as plaques) and is thought to be a major factor driving Alzheimer's neurodegenerative effects.
CRI provides a pilot grant to Jean - Pierre Mach for preclinical studies to test a new cancer immunotherapy strategy using anti-tumor antibody fragments conjugated to antigenic MHC / peptide complexes.
Through two separate grants, Dr. Bhardwaj is exploring two strategies to make immunotherapy even more effective for patients.
We have identified a major pathway by which these kinds of cells try to disable immune cells, and formulated a strategy for exploiting that weakness,» says the study's principal investigator, Kunle Odunsi, MD, PhD, FRCOG, FACOG, Deputy Director and Chair of Gynecology at Roswell Park, and Executive Director of its Center for Immunotherapy.
Scientists come up with a simpler, more efficient strategy for making multivirus - targeting T cells for immunotherapy.
We are developing cutting - edge discovery platforms and product strategies for effective cancer immunotherapies that we believe take into consideration the limitations of other approaches, as well as leveraging different mechanisms of action to address the risk of reliance on a single approach.
Their work encompasses several strategies, including: developing FL - HCC animal models to characterize tumor - immune interactions, exploring if a mutated protein associated with FL - HCC could be targeted by immunotherapy, identifying immune checkpoints that could potentially serve as targets for immunotherapy as well as biomarkers for analyzing patients, and evaluating the effectiveness of immunotherapy strategies against FL - HCC patient samples in the lab.
This has led to a successful strategy for cancer immunotherapy: block the pathways that tumors use to turn off the immune response.
The intent of the effort is to build off the identified immunologic factors that may be modulated to improve immunotherapy for CRC patients, with the goal that the biomarkers and treatment strategies identified in the manuscript will become part of the routine management of colorectal cancer (CRC).
Additionally, this team hopes to identify features that drive patient responses to immunotherapy and gain insight into additional strategies for converting immunotherapy resistant tumors into tumors that respond to treatment.
Promising strategy for advanced melanoma: intralesional therapies plus systemic immunotherapies.
Immunotherapy's time is now, and he is excited to be working at the forefront of strategies that could make the approach a treatment option for any patient in need.