An eQTL mapping approach reveals that rare variants in the SEMA5A regulatory network
impact autism risk.
Not exact matches
Recently, researchers from Harvard and Mt Sinai found that both environmental chemicals and environmental stress can disrupt the development of a fetus» brain and negatively
impact the baby's long - term health, even increasing the
risk of
autism spectrum disorders.
Page and his colleagues, who use animal models to understand how
autism risk factors
impact the developing brain and to identify potential treatments for the condition, have found that animals with mutations in the
autism risk gene phosphatase and tensin homolog (Pten) mimic aspects of
autism, including increased brain size, social deficits and increased repetitive behavior.
The study was funded by a High
Risk High
Impact grant from the
Autism Speaks Foundation.
Initially applied to polygenic myocardial infarction and coronary heart disease
risks, the methodology can now be applied to a range of high -
impact disorders such as schizophrenia, Type 2 diabetes,
autism, and cancer.
Researchers at the Carolina Institute for Developmental Disabilities tracking age - related issues of
autism identified an increased
risk of Parkinson's disease in this high -
impact paper.
There are also suggested links to other
impacts on the neurological development of children, including an increased
risk of
autism spectrum disorder.