While the impact on the R&D tax credit would mostly
impact large public companies at first, those changes will over time play a role in how future startups spend money on innovation.
Not exact matches
Capital
Impact Partners is among the
largest of the roughly 1,000 CDFI's in the U.S., having invested $ 1.8 billion in senior care, affordable housing, education and
public nutrition projects in distressed and low - income communities across the country.
I don't know how much is spent annually on treating erectile dysfunction, but clearly, finding treatments and cures for neurological disorders has a profound positive
impact on the
larger economic and
public good.
DBL Investors, a $ 225 million
impact investment firm in San Francisco, had all of those factors going for its investment in SolarCity, now the
largest solar installer in the country, worth nearly $ 6 billion two years after its initial
public offering.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and
public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a
larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange
impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
But the fact that the Fed came up in the debate was a positive; «there's no reason such an important
public institution — one with such a
large impact on people's lives — should be off limits in political debates.»
Grounded in Boston Fed research, the Challenge encourages leaders from the
public, private, and nonprofit sectors to advance proposals that tackle complex challenges facing smaller post-industrial cities and achieve
large scale
impact across communities.
CCBE examined the
impact of the «Comply or Explain» requirement on the diversity of Canada's
largest public issuers and found that improvements in the representation of women on boards continues to improve slowly, but Comply or Explain doesn't appear to be a sufficient motivator on its own.
«It could help [lower beef prices] in the short - term, but it remains to be seen how
large of a supply would be made available to know if it would have definite
impact,» says Christin Fernandez, director of media relations and
public affairs at the National Restaurant Association.
Florida State should be an even
larger favorite, but
public perception in clearly
impacting this line.
They can exert some influence at home, but the
larger public policy choices that
impact them are made by adults.
It's like a perpetual town hall where the
public can now
impact the conversation regularly and sometimes in a very
large way.
The Master Settlement Agreement is a $ 10 billion settlement between various governments and the five
largest tobacco companies related to the
impact of tobacco use on
public health.
The NASUWT, the
largest teachers» union in the UK, has launched an advertising campaign aimed at parents and the
public, highlighting the
impact of the Conservative - driven Government education policy on children and young people.
The plan will
impact nearly all positions at Long Island's
largest public research university that are funded by the state budget.
Fields is one of more than 400,000 residents of the New York City Housing Authority (NYCHA), the country's
largest public housing system, who stands to be
impacted by the executive order signed by Governor Andrew Cuomo declaring a state of emergency this past Mon., Apr. 2nd.
Also at 10:30 a.m., the Assembly will hold a
public hearing to examine the
impact of the Renewable Portfolio Standard program and the proposed creation of the Clean Energy Fund for the advancement of
large scale renewable energy production, Assembly Hearing Room, 250 Broadway, Room 1923, 19th Floor, Manhattan.
One of the
largest impacts of immigration seems to be on
public perceptions.»
But their passionate opposition to the chemical plant generated an explosion of
public anger that forced a halt in construction, pending further environmental
impact studies by authorities in Beijing, and produced
large demonstrations June 1 and 2, drawing national publicity.
Beyond its use as a tool against
large financial institutions, Schneiderman has used the act as a basis for a probe into ExxonMobil, arguing that its alleged failure to disclose to its shareholders and the
public research that showed the potential
impact of climate change constituted a Martin Act violation.
«In view of the
large number of people who consume processed meat, the global
impact on cancer incidence is of
public health importance.»
They argue that while
large public investments in dams and flood defences, for example, must account for the possibilities of how weather might change in the future, this should not prevent short - term thinking to address more immediate vulnerability to inevitable high -
impact weather events.
Jury member Penny Heaton, director of vaccine development at the Bill & Melinda Gates Foundation, said CureVac's RNA technology had «the potential for a
large and positive
impact on
public health,» in a statement released by the company on 10 March.
To test the
impact of
public commitment on health behavior, the researchers had physicians post a
large letter about inappropriate antibiotic prescription in their exam rooms.
Stephanie Anzman - Frasca, Ph.D., of ChildObesity180, Tufts University, Boston, and co-authors used data from 446
public elementary schools in a
large, urban school district in the United States to look at the
impact of BIC on participation in the School Breakfast Program (SBP), school attendance and academic achievement.
The use of the word «medical» seems to have an even
larger impact on
public attitudes.
In a collaborative research effort between Tulane University School of
Public Health and Tropical Medicine and Harvard T.H. Chan School of
Public Health, Qi and colleagues analyzed the
impact of tooth loss in
large studies of adults, aged 45 to 69 years, in which participants had reported on the numbers of natural teeth they had, then in a follow - up questionnaire, reported recent tooth loss.
The JAMA Pediatrics study is the first of a
large - scale
public program to assess
impacts on mid-life educational attainment and the contributions of continuing services in elementary school.
Measles causes significant absence from school or work and has a much
larger impact on people's daily lives than illnesses like flu or chicken pox, according to a new study by researchers from the London School of Hygiene & Tropical Medicine and
Public Health England.
«It is challenging to lose weight, but if women commit to losing 10 percent of their body weight and sustain that over time, it can have a
large impact on overall risk factors associated with heart disease and diabetes,» said Cynthia A. Thomson, Ph.D., R.D., co-author and Professor in the Mel and Enid Zuckerman College of
Public Health and Director of the University of Arizona Canyon Ranch Center for Prevention & Health Promotion in Tucson.
•
Large - scale
public preschool programs that are of high quality can have a substantial
impact on children's early learning.
Of greater
impact to the general
public would be loss of water for critical cooling processes at
large facilities like power plants.
He has dedicated his
public health career to service, volunteering and advocating for range of global, national and regional causes
impacting on health, education, housing, among other societal issues and has mentored a
large number of future
public health professionals.
Large fires are becoming more common and severe, and the smoke from these fires has serious
public health
impact
Climate change is a pervasive source of risks to human systems, with potentially
large impacts upon the economy,
public health, and national security.
Because of the high consumption of coffee, even small effects on cancer occurrence in persons could have a
large impact on
public health.
What the Saul Zaentz Charitable Foundation has done is unique and inspirational — it is enabling the launch of a very
large - scale study with the potential to generate insights akin to what the field of
public health has produced, because of population - based research, around pressing issues, such as heart disease and the
impact of smoking or lead exposure on health and development.
Importantly, the schools attended by students in our sample include both open - enrollment
public schools operated by the local school district and five over-subscribed charter schools that have been shown to have
large, positive
impacts on student achievement as measured by state math and English language arts tests.
Tom Payzant, the veteran superintendent who heads up Boston
Public Schools, says
large school districts get funding from a variety of philanthropic organizations, but he has had to work hard to persuade these funders to align their efforts to support a system - wide vision of how to improve education and avoid contributing to what he calls «project-itis,» which is just a series of ad hoc donations that make givers feel good but have little
impact on students.
The rubric reflects both a scholar's
larger body of work and their
impact on the
public discourse last year.
While the
public discussion around college usually focuses on the price paid by students, recent work by economists David Deming and Chris Walters suggests that declines in the amount colleges and universities spend may have a
larger impact on student outcomes.
In a new
Public Impact policy brief, A Better Blend: A Vision for Boosting Student Outcomes with Digital Learning, which we co-authored with Joe Ableidinger and Jiye Grace Han, we explain how schools can use blended learning to drive improvements in the quality of digital instruction, transform teaching into a highly paid, opportunity - rich career that extends the reach of excellent teachers to all students and teaching peers, and improve student learning at
large scale.
When presented with research evidence that claims «students learn no more in private schools than in
public schools,» support for school vouchers dropped by 10 percentage points, an
impact almost as
large as the President's.
Despite the numbers, the school choice programs are not
large enough to have had more than a limited statewide
impact on the millions of students attending Florida's
public schools.
In other words, even though the average charter has a zero or negative
impact on test scores, there are more charters with very
large positive or very
large negative test - score
impacts than there are traditional
public schools with such extreme outcomes.
The PZ Reach Scholarship aims to support educators working in underserved settings — for example, Title I
public schools, areas with high rates of identity - based violence, or communities with
large numbers of families
impacted by immigration and / or displacement — to attend Project Zero Classroom.
In most cases, the types of policy distinctions that loom
large among policy experts have little
impact on
public opinion.
This is the case in Boston, where researchers» careful tracking of six charter high schools over the last decade has shown that those charters have a
large and positive
impacts on MCAS scores as compared to the city's conventional
public high schools.
-- April 8, 2015 Planning a High - Poverty School Overhaul — January 29, 2015 Four Keys to Recruiting Excellent Teachers — January 15, 2015 Nashville's Student Teachers Earn, Learn, and Support Teacher - Leaders — December 16, 2014 Opportunity Culture Voices on Video: Nashville Educators — December 4, 2014 How the STEM Teacher Shortage Fails U.S. Kids — and How To Fix It — November 6, 2014 5 - Step Guide to Sustainable, High - Paid Teacher Career Paths — October 29, 2014
Public Impact Update: Policies States Need to Reach Every Student with Excellent Teaching — October 15, 2014 New Website on Teacher - Led Professional Learning — July 23, 2014 Getting the Best Principal: Solutions to Great - Principal Pipeline Woes Doing the Math on Opportunity Culture's Early
Impact — June 24, 2014 N&O Editor Sees Solution to N.C. Education «Angst and Alarm»: Opportunity Culture Models — June 9, 2014
Large Pay, Learning, and Economic Gains Projected with Statewide Opportunity Culture Implementation — May 13, 2014 Cabarrus County Schools Join National Push to Extend Reach of Excellent Teachers — May 12, 2014
Public Impact Co-Directors» Op - Ed: Be Bold on Teacher Pay — May 5, 2014 New videos: Charlotte schools pay more to attract, leverage, keep best teachers — April 29, 2014 Case studies: Opening blended - learning charter schools — March 20, 2014 Syracuse, N.Y., schools join Opportunity Culture initiative — March 6, 2014 What do teachers say about an Opportunity Culture?
Issued in the spring of 1972, the panel's final report predicted that, unless steps were taken, alternatives to
public schools would all but disappear; the greatest
impact, the report noted, would be felt in «
large urban centers, with especially grievous consequences for poor and lower middle - class families in racially changing neighborhoods where the nearby nonpublic school is an indispensable stabilizing factor.»