Sentences with phrase «impact of a new environment»

Not exact matches

You're not supporting the manufacturing (and subsequent carbon footprint) of a brand new product or the location and transportation costs (both financial and environment - impacting) to get it to your front door.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«Barring any big changes in the environment, we expect Chinese investment in Canadian real estate to increase in 2016, and the impacts of that investment to be spread more widely as these buyers move into new markets,» Charles Pittar, CEO of Juwai.com.

In this Raddon Report, we look at what has changed, who will be affected, the impact of the change on homeowners, and what institutions can do to market their mortgage and equity products in this new environment.

Poorly camouflaged insects can kick off a cascade of ecological impacts, new CU - Boulder study finds October 21, 2013 • Natural Sciences, Research, Academics, Environment

Natural Selection of random mutations is not a Fairy Godmother who can be waved in at everymoment; the «environment» which «selects» is the total impact of other being upon one being, and the selection is the better «survival value» of the new mutant.

Most Provocative: Andrew Jones with «9 Reasons NOT to Plant a Church in 2012» «The measurement criteria of the church planting project, focusing on numbers of attenders and momentum of new church launch, is too narrow, too shallow, un-holistic and ignores more vital measurable signs of a transformed society in its various spheres (economic, environmental, social, impact outside the church environment, etc).»

Like fellow Bay area start - up Geltor, Perfect Day is one of a new breed of companies in the «cellular agriculture» business — using genetically engineered yeasts that have been «programmed» to produce proteins or other ingredients found in plants or animals - on an industrial scale, without raising animals, and with less impact on the environment.

«Beverage companies have always been leaders in the development of new and innovative ways to reduce industry impact on the environment,» said Susan Neely, American Beverage Association president and CEO.

A new documentary film from Canada aims to expose the impact of livestock farming on the environment.

The packaging of consumer goods impacts the environment, so we employ efforts to use the minimal amount of packaging necessary while maintaining food safety and quality, and work with suppliers to find new solutions to use less packaging or materials that are recycled or recyclable.

Some football helmet manufacturers suggest that players who wear their helmets - especially new models - may be at lower risk of concussion than those who wear competitors» models or older helmets, basing their claims on how well the new or newer helmets absorb and lessen some of the impact forces that cause concussion in biomechanical studies performed in the controlled environment of the laboratory.

The new Camelot Community Center incorporates a variety of strategies to conserve energy, reduce heating / cooling loads, and that lessen the impact on the environment:

The purchase of a new mattress can have a lasting impact on the environment.

There are already, new National Assembly Business Environment Roundtable (NASSBER) research findings projecting that our priority bills will have an output impact equivalent to an average of 6.87 per cent of GDP over a five - year period on the economy.

As with any major transport project, there were environmental concerns about the impact of a new railway through the centre of the city - both in terms of the natural and built environments.

The Manhattan Institute's Center for Energy Policy and the Environment releases a new report on the economic impacts of closing and replacing Indian Point.

Department of Environmental Conservation Commissioner Alexander «Pete» Grannis was fired last week for having the courage to speak the truth about the impact threatened layoffs would have on the integrity of his department's responsibility to protect the environment and New Yorkers.

Tara DePorte of the Lower East Side Ecology Center said her organization has been training students and quite a few New Yorkers who have lost their jobs to help restaurants reduce their impact on the environment.

The capital gains environment may have an even bigger impact on the commercial real estate sector, said Robert Knakal, chairman of Massey Knakal Realty Services, noting that several of his clients have decided to sell this year because they anticipate the rate will go up in the new year.

«The recent statewide growth in and impact of tax exempt entities severely erodes the tax base of local governments and school districts, unfairly transfers the tax burden to remaining homeowners and businesses, and further compromises New York's position as a fair and competitive environment in which to live and invest,» Teresi said in October as part of his budget address.

The risk of catastrophic danger to the environment, the health of New York State residents and adverse economic impacts that result from hydraulic fracturing far outweigh the potential for job creation and promotion of a natural gas alternative to oil.

While these advances laid the groundwork for understanding the «ins and outs» of the epigenome, the emergence of the new fields of toxicoepigenetics and environmental epigenetics has provided the opportunity to enhance our understanding of how chemical and non-chemical environments impact health and susceptibility.

As the corps considers public comment on the new permit, Pew is spotlighting living shorelines across the country, said Laura Lightbody, program director for the foundation's efforts aimed at reducing the impact of weather - related catastrophes, such as floods and hurricanes, on the U.S. economy, communities and environment.

Its strategy consists of four key components: 1) Priority identification — we respond to the crop biotechnology needs and priorities identified by developing countries; 2) Technology appraisal — we work to identify, evaluate, and facilitate the acquisition of new crop biotechnology applications; 3) Project implementation — we implement a portfolio of crop biotechnology projects that have a potential for near - term impact in food, feed, fiber crops, and forestry; and 4) Services for the enabling environment — we provide advice and services to assist in the development of an enabling environment to support the safe application of crop biotechnology.

The harmful impact of urban air pollution could be combated by strategically placing low hedges along roads in a built - up environment of cities instead of taller trees, a new study has found.

The need to foresee the probable consequences of human activities has generated new techniques for monitoring environmental change and for assessing the impact of present and proposed actions upon the natural and social environment.

«Cities need to «green up» to reduce impact of air pollution: The harmful impact of urban air pollution could be combated by strategically placing low hedges along roads in a built - up environment of cities instead of taller trees, a new study has found.»

«Initiating new approaches to product design and manufacturing processes can affect a product's cost, desirability to consumers and the impact of the product on our environment,» said Raz.

As New York, New Jersey and the rest of the northeastern U.S. come to grips with Hurricane Sandy's impact, some leaders there are realizing that two debilitating hurricanes in as many years there are a sign that infrastructure there needs rethought, not just rebuilt.Postmortem assessments of Sandy's impact should include a «fundamental rethinking of our built environment,» New York Governor Andrew Cuomo said Wednesday during a press conference.

A team of researchers, led by the University of Minnesota, has invented a new soap molecule made from renewable sources that could dramatically reduce the number of chemicals in cleaning products and their impact on the environment.

Without land - use policies to limit its environmental footprint, the impacts of cannabis farming could get worse, according to a new study published in the November issue of Frontiers in Ecology and the Environment.

A new report by authors from UCLA School of Law's Emmett Center on Climate Change and the Environment and UCLA's Institute of the Environment and Sustainability explores the sources and impacts of plastic marine litter and offers domestic and international policy recommendations to tackle these growing problems — a targeted, multifaceted approach aimed at protecting ocean wildlife, coastal waters, coastal economies and human health.

A new report by the Environmental Change Institute (ECI) at the School of Geography and the Environment at the University of Oxford concludes that better governance could have lessened the impact on the poorest and most vulnerable, and affected populations have been let down by the authorities in the past.

Professor Michael Benton from the University of Bristol, another co-author of the study, said: «This work illustrates a case of the impact of climate change on the evolution of animal biodiversity, and shows that for crocodilians, warming phases of our earth's history constitute ideal opportunities to colonise new environments.»

The Trinity group's work has provided the new hypothesis that impact craters were ideal environments to facilitate the reactions that saw the first «seeds of life» take root.

«Alien plants often gain advantages in their new environment because they lack natural enemies, and in this case the lack of strong competitors amongst alpine plants may be the key to success for generalist native species,» says ecologist Ann Milbau, assistant professor at the research station Climate Impacts Research Centre in Abisko, Sweden.

Moving the chemical complexity of the ocean to the laboratory represented a major advance that will enable many new studies to be performed,» said Kimberly Prather, Distinguished Chair in Atmospheric Chemistry at the University of California, San Diego and director of the Center for Aerosol Impacts on Climate and the Environment, who led the team of more than 30 scientists involved in this project.

In a project funded by the German environment ministry, he has attempted to model the environmental impact of a series of flights from Frankfurt to New York, following the fate of emissions for ten days.

Morteza Khaledi, dean of UTA College of Science, noted that Dr. Passy's research breaks new ground among biologists studying how biological communities respond to their environment and contributes to the university's increasing focus on global environmental impact within the Strategic Plan 2020: Bold Solutions Global Iimpact within the Strategic Plan 2020: Bold Solutions Global ImpactImpact.

Vinetz said the next step will be to begin exploiting the genomic information «for vaccine and diagnostics development, experimental approaches to understanding mechanisms of disease pathogenesis and how Leptospira persist in the environment, all critical for developing new public health interventions aimed at reducing the global impact of this important but neglected zoonotic disease.»

The international working group, which includes geologists Jan Zalasiewicz, Mark Williams and Colin Waters, from the University of Leicester's School of Geography, Geology and the Environment and archaeologist Matt Edgeworth has, since 2009, been analysing the case for formalisation of the Anthropocene, a potential new epoch of geological time dominated by overwhelming human impact on the Earth.

NASA»S Lunar Reconnaissance Orbiter (LRO) spacecraft has spied a new crater on the lunar surface; one made from the impact of NASA's Lunar Atmosphere and Dust Environment Explorer (LADEE) mission.

The positive outcome «was a wonderful and rather unusual example of introducing a microbial community into a new environment,» said Jansson, «where it was able to establish and have a major impact.»

The effects of human activity have long been cited as a primary cause of global climate change, but new research from NASA has revealed that our use of technology also appears to be having an impact not just on the planet, but on Earth's near - space environment as well.

The REF exercise also recognised our excellent research environment and how our research is having a genuine influence of the real lives of people, as evidenced by a series of impact cases studies, from new drugs and inventions to public policy.

But I do feel that having a daughter of my own has led me to a whole new «eco-awakening» — inspiring me to be even more conscious of our impact on the environment.

Finally, they also made sure all of the subjects got acquainted with the equipment beforehand to make sure the new environment didn't have much of an impact on their calorie expenditure.

But equally, a failing environment can be reflected by a poor reputation and loss of business.It can not only be difficult to win new training contracts with employers but the impact on staff can be deeply felt: it always hard to retain experienced staff while attracting high calibre people to poorly performing college, for example.

Toddlers vary widely, however, in the rate at which they learn new words.1 A team of Harvard Graduate School of Education researchers set out to ask whether and how children's language environment can impact vocabulary development.