Sentences with phrase «impact on cell function»

Alternatively, evolutionary approaches have been used to identify functional regions as those that are likely to have a measurable biological impact on cell function if perturbed.

Not exact matches

This is a new era where we are now able to test whether a dose of stem cells delivered directly to the injured site can have an impact on motor or sensory function,» says Fessler.

They impact on signal transmission from cell to cell, but also affect intracellular communication,» explains Professor Robert Ernst, whose research group at the BMLS has been on the trail of fats» hidden functions for years.

And what impact does tissue donor status have on stem cell function?

For decades, researchers have assumed that these tRNAs had little impact on the function of the cell.

While humanized mouse models provided a logical first approach to examine in vivo efficacy of CXCR4 disruption, this system does not make it possible to fully assess the functional impact of CXCR4 loss on CD4 + T cell function.

Dr. Kulkarni's research focuses on investigating signaling pathways impacting growth and function of pancreatic islet cells with the long - term goal of improving therapeutic approaches for the treatment of type 1 and type 2 diabetes and obesity - associated conditions.

They further show that, by regulating lipid metabolism, a cell is able to switch its immune phenotype by using transcriptional mechanisms and that the lipid environment has an important impact on immune cell function.

The impact of Ex Vivo clinical grade activation protocols on human T - cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.

(2006) Potential Impact of Glial Hypertrophy and Proteoglycan Changes on Retinal Ganglion Cell Function in the DBA / 2 Mouse Model of Glaucoma (Investigative Ophthalmology & Visual Science, 47: ARVO E-Abstract 1576).

It impacts cells on the cellular level and increases mitochondrial function and ATP production.

Due to its impact on DNA, methylation plays a role in many other fundamental functions: creating the building blocks for DNA and RNA, hormones, neurotransmitters, cell membranes, protein synthesis, and others 2, 4.

Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways in which nutrients and water are transported within animals, including humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment in different ways and that adaptation may lead to evolution Recognise that light appears to travel in straight lines Use the idea that light travels in straight lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels in straight lines to explain why shadows have the same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer with the number and voltage of cells used in the circuit Compare and give reasons for variations in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit in a diagram

The scientists finding, published in the Journal of the American Medical Association, report that there is a significant impact of omega - 3s on cell support and cell functioning.