The investigators utilized a targeting method called RNA interference (RNAi) which, when delivered via these natural nanoparticles or exosomes, zero in on mutant KRAS in pancreas cancer cells,
impacting tumor burden and survival in multiple pancreas cancer models.
Not exact matches
«This study is an important step toward understanding the
impact of
tumor mutation
burden and PDL - 1 in immunotherapy response.
The objective was further explore and analyze the
impact on prognosis of
tumor size and of the different T descriptors; the prognostic significance of
tumor burden in hilar and mediastinal lymph nodes; and the confirmation of the revised M1 categories (M1a and M1b) of the seventh edition of the classification along with the prognostic
impact of number and anatomic location of metastases.