In humans, a similar protein complex called CSN and its subunit CSN6 is now believed to be a cancer - causing gene that
impacts activity of another gene (Myc) tied to tumor growth.
Not exact matches
«Environmental events can dramatically
impact gene activity,» explains reproductive endocrinologist Frederick vom Saal
of the University
of Missouri - Columbia.
BET proteins can have a huge
impact on
gene activity because they belong to a class
of molecules called epigenetic readers, which recognize special marks on DNA - protein complexes and attract
gene - activating proteins to those spots.
Because they influence the
activity of many «downstream» genetic targets, small changes in the expression
of these regulatory
genes can have an enormous
impact.
Group research aims to study the relations between nutraceuticals, physical
activity, intracellular mechanisms,
gene expression and microbiota using a translational approach to characterize the
impact in the whole body
of metabolic interactions studied in individual organs and tissues (in vitro / ex vivo: skeletal muscle, heart, bone, liver and kidney).
Studies have shown that the
activity of hundreds
of genes responsible for enzymes that break down fats and detoxify prescription drugs, are negatively
impacted by stress.