(iii) Many cancer patients, in particular those with advanced stages of the disease, exhibit altered whole - body metabolism marked by increased plasma levels of inflammatory molecules,
impaired glycogen synthesis, increased proteolysis and increased fat utilization in muscle tissue, increased lipolysis in adipose tissue and increased gluconeogenesis by the liver.
Not exact matches
Surprisingly, the researchers found that
glycogen synthesis does not require a protein called glycogenin, and that high
glycogen levels actually
impair endurance muscle performance in mice.
Furthermore, the model has been used to study the molecular background for the
impaired glucose transport and
glycogen synthesis associated with insulin resistance in skeletal muscles.
Studies have shown that alcohol
impairs the
synthesis of
glycogen in the liver and oxidative muscles - negatively impacting both performance and recovery.
Decreased
glycogen synthesis, along with
impaired sleep and increased dehydration all support the negative impacts alcohol has on recovery.