Sentences with phrase «impaired gut barrier function»

A maladapted stress response is thought to contribute to IBS flares through several mechanisms, including impaired gut barrier function, changes in gut flora, changes in gastrointestinal motility and secretion, decreased mucosal blood flow, and decreased ability to heal and recover from damage.

Stress in itself, in otherwise healthy individuals subjected to intense physical training, has been shown to impair gut barrier function, (9) likely through effects on the stress hormone cortisol.

Not exact matches

Taken together, these findings demonstrate that age - related changes in the gut microbiome weaken the intestinal barrier, leading to the release of bacterial products that promote inflammation, impair immune function, and reduce lifespan.