Sentences with phrase «impairment in ageing mice»
A genetic switch linked to memory impairment in ageing mice has been flipped back on, restoring failing brains to a more youthful state.
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Although we did observe positive effects on some aging traits, such as memory impairments and reduced red blood cell counts, our studies showed that similar drug effects are also seen in young mice, indicating that rapamycin did not influence these measures by slowing aging, but rather via other, aging - independent, mechanisms.»
We report here a reversal of cognitive impairment in aged huAPP / PS1 mice by J147 and provide evidence that these beneficial effects are due to the ability of J147 to normalize several different aspects of AD pathology, likely through the up - regulation of the neurotrophin pathway.
Yet another primary interest is in the genetics of hearing and deafness disorders using mouse models of human deafness disorders and genome - wide association studies in age - related hearing impairment.
Estradiol increased performance in young and aged mice under minimized organizational demand, but failed to improve the age - associated memory impairment and diminished performance in young mice under high organizational demand.