This week, Fior, who is at the Champalimaud Centre for the Unknown in Lisbon, and her colleagues reported growing
implanted human tumor cells in zebrafish larvae.
Not exact matches
Shih, Wang and their colleagues tested fostamatinib's power to reduce
tumor size in mice
implanted with
human ovarian cancer
cells that were resistant to paclitaxel.
Next, the team tested the GD2 CAR - T
cells in mice whose brainstem was
implanted with
human DIPG
tumors, an experimental system that Monje's lab pioneered.
Now, scientists have modified Salmonella bacteria to trigger a particularly powerful immune response against
human cancer
cells implanted in mice, shrinking the
tumors and — for the first time — preventing them from metastasizing.
We chose this model because 1) it more closely recapitulates features of
human pancreatic cancer than do s.c. -
implanted tumors, 2) it can be used in immunocompetent mice to permit assessment of immune responses, and 3) the
cells grow in vivo with predictable kinetics (34).