Sentences with phrase «implicating immune cell function»

Not exact matches

IDO1 has been implicated in immune modulation through its ability to limit T cell function and engage mechanisms of immune tolerance, and as such preventing tumor rejection.

Methylation, a fundamental epigenetic process whereby carbon groups are attached to DNA to either silence it or promote its expression, is quintessential to cellular processes including detoxification, metabolism, neurotransmitter synthesis, mitochondrial energy production, central nervous system function, cell cycle regulation, cellular integrity, and immune homeostasis — and derangements in methylation have been implicated in many diseases (Robertson, 2005).