Sentences with phrase «important gene for»

Intriguingly, an identical homozygous mutation was identified in a human patient with recessive retinitis pigmentosa, the human equivalent of PRA, and established the novel retinal gene, PRCD, as an important gene for the maintenance of rod photoreceptor structure and function across species.

This immune system gene is also found in humans and other animals, and is thought to be the most important gene for inherited immunity.

She and her colleagues found Karma, a mobile piece of DNA known as a transposon, inserted in the middle of an important gene for normal oil - palm fruit development called DEFICIENS.

Bach2, an important gene for inducing memory B cells, may become an important target in vaccine strategies.

Fun fact: Unlike others of its kind, A. hoosieri lacks a debilitating mutation in the rhodopsin gene, which is an important gene for vision.

The presence of several mutations in four important genes for the brain's synapses can be associated to Obsessive Compulsive Disorder in humans.

Not exact matches

For Dawkins, by far the most important aspect of biological nature is the ability of certain stretches of DNA («genes») to engender faithful copies of themselves, under conditions that prevail.

And on the world - food security front, ARS» Stuttgart center is closing in on genes that regulate rice's uptake and storage of iron, thiamine and other important vitamins and minerals — a pursuit that could bolster the nutritional value of this cereal grain crop as a staple food for roughly half the world's population.

This massive dataset is a powerful resource for understanding natural genetic variation in rice as well as for large - scale discovery of new genes associated with economically important traits.

The OsAux1 gene is involved in the transport of the hormon auxin, which is important for virtually every aspect of plant growth and development.

«Orphan genes are probably extremely important for rapid, short - term adaptations, when a species needs something new and innovative.

«We want to know which are the most important genes that are responsible for the improved learning and recovery of memories,» she adds.

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

When looking for genes that might play important roles in the metabolism of healthy and cancerous liver cells, Wang and his colleagues became interested in a gene called SLC13A5, which produces a protein that transports citrate into cells.

The three - day treatment reversed social deficits in mice deficient in a gene called Shank 3, an important risk factor for ASD.

What's more, genes known to be important for cancer were repeated between 60 and 100 times in the monster, massively amplifying their effect.

The gene for NPAS4 was a top hit, and significant for an important reason: it is an early - onset gene, meaning that its effects could be exerted on the brain rapidly unless HDAC5 was there to inhibit it — just the molecular event Cowan and his team were seeking.

But when they tried to pinpoint the genes involved, something unexpected happened: they stumbled on C1q, a gene for a protein important in the body's immune system.

Mitochondria contain genes coding for proteins important in energy production.

University of Adelaide School of Molecular and Biomedical Science PhD student, Deborah Toledo - Flores, says: «the most important aspect of this work for us was to identify more genes on platypus Y chromosomes to reveal new leads about potential sex determining genes in these animals.»

For the study, the researchers created a line of zebrafish with defective immune systems by inserting a mutation into a gene required for development of an important component of the immune systFor the study, the researchers created a line of zebrafish with defective immune systems by inserting a mutation into a gene required for development of an important component of the immune systfor development of an important component of the immune system.

Tweaks to genes important for development may account for both the giraffe's stature and turbocharged cardiovascular system, researchers report May 17 in Nature Communications.

«Our new data is scientifically important because ataluren restores activity to genes inactivated by nonsense mutations, and as a result, it has the potential to do so much for a large number of very complex genetic disorders,» Jacobson said.

«This gene has been on the agenda for human sex development, but it's quite important that a case has now been reported.»

The gene encodes a protein that is important for intracellular transportation.

Other directions for future research, Liu said, include looking at the role of CLOCK in more forms of the disease, learning more about exactly how CLOCK affects neural circuits to disrupt adequate inhibition of excitatory neurons, and examining whether any of the genes that CLOCK regulates are especially important in the disorder.

«DNMT3A places itself preferably in close vicinity to genes that play an important role for development and makes sure that the DNA methylation around these genes is maintained,» explains Massimiliano Manzo, lead author of the study.

Experiments with these mice suggest TREM2 is important for steering microglia toward amyloid and turning on genes that rev up their cleanup capabilities.

«I think it's important [for journals] to be discussing this, but I think it's unrealistic to think that journals can and should play the role of the sole enforcer,» says Claire Fraser, director of The Institute for Genomic Research in Rockville, Maryland, which posts a range of microbial gene sequences online.

These drug - bug interactions could make microbial genes just as important as a person's genes for predicting how a drug will affect someone, says Matthew Redinbo of the University of North Carolina at Chapel Hill.

Then they explored what happened to this pattern of gene expression when beta blocker treatment was implemented, and what they found not only surprised them, but could have important ramifications for future treatments of heart disease.

Through these multiple discoveries, the Gladstone scientists noticed that the reprogramming process involves many genes and proteins important for cancer biology.

«The study analysed the genome of these eight species and performed comparative analysis of animal genes important for signalling, neuronal and ionic conduction, epithelia, immunity and reproduction, which are the basic functions associated to multicellularity,» she adds.

Nevertheless,» [the] study is very important because it demonstrates for the first time that we can use gene therapy to transform cells in the brain into ones that will secrete GDNF,» says Jeffrey Kordower, a professor of neurological sciences at Rush Presbyterian Medical Center in Chicago.

The Salk researchers discovered that deletion of the WRN gene leads to heterochromatin disorganization, pointing to an important role for the WRN protein in maintaining heterochromatin.

In all CS cases, said Morrow who treats autism patients at the E. P. Bradley Hospital in East Providence, boys have a mutation on the SLC9A6 gene on the X chromosome that disables production of a protein called NHE6 that is important for neurological development.

For any particular cell, such as a skin or brain cell, much of this genetic information is extraneous and must be packed away to allow sufficient space and resources for more important genFor any particular cell, such as a skin or brain cell, much of this genetic information is extraneous and must be packed away to allow sufficient space and resources for more important genfor more important genes.

Some scientists disagreed over whether certain types of gene - editing would be important for helping patients, with one prominent researcher contending the technology would not often be needed, while another described dire current clinical needs for it.

«The trial is important for gene research and may be a proof of principle that targeting the most common mutation in cystic fibrosis is an effective approach for treatment of most patients,» Gentzsch said.

«Clearly there are many important roles for these genes in facial, skin and, organ development, and we're only just starting to catalogue them,» said Russ P. Carstens, MD, an associate professor of Medicine (Renal - Electrolyte and Hypertension Division) and Genetics.

«Although zebrafish look quite different from humans, they share an astonishing 70 percent of their genetic material with humans, including genes important for the formation of new heart muscle,» Yin said.

What's more important for avoiding genetic diseases is boosting access to gene testing so people can be more aware they are carriers for disease, he said.

The results from the study also showed that genes that increase the risk for cancer and diabetes, or are important for the immune response or sperm quality, are affected by smoking.

«By identifying the areas of the genome that are directly involved in the reprogramming, we have also identified an important factor in the process — the gene regulatory protein KLF11 (Kruppel Like Factor - 11), which is found in all fat cells, and we have shown that it is required for the reprogramming to take place.»

That's why sequencing the genome was important, he said, because it will help identify all the genes and enzymes in the genome needed for hydrocarbon production and control of this production.

Julian Isla, Executive Director of DSF - EU, stated: «One of the most important things for patients with genetic disorders and their families is to be able to give a name to the gene causing their disease.

«As a result of the previous study, we reported that SUMO is probably important for controlling expression of active genes because we found it on every gene we looked at, but only when they were turned on,» notes Rosonina.

The gene may have been important for the evolution of big human brains.

Those deletions tended to involve genes that affect cilia, cellular structures that are important for signaling and patterning in embryonic development.

The findings show an important role for epigenetics in bumblebees, and suggest that whether a gene is turned off or on depends on whether it comes from the father or the mother.