Not exact matches
When prion
protein molecules are sequestered by their misfolded counterparts, they can no longer work as a
scaffold for all these molecular interactions, which impairs the mechanisms evoked by the brain chemicals
important for mood.
Receptor interacting
protein kinase 1 (RIPK1) has
important kinase - dependent and kinase - independent
scaffolding functions that activate or prevent apoptosis or necroptosis in a cell context — dependent manner.
It will be
important, Panne says, to dissect in detail how
scaffold proteins, such as the CBP and p300 co-activators, contribute to the rich gene regulatory language, how such chromatin modifiers are targeted to the genome, how their activity is regulated, and how chromatin modifications contribute to the signaling reaction.
Collagen is the main structural
protein in your skin; it provides a
scaffolding around which all
important proteins and tissues can be built.