Charting the network of discoveries that led to the development of
important therapeutic drugs, the investigators revealed that, up to now, the path to a cure has required thousands of scientists and many decades.
Not exact matches
«If nanoparticles are carrying a
drug to deliver, different uptake could mean different
therapeutic efficacy and other
important differences, such as safety, in clinical data.»
Since small, early - stage cancers are the most responsive to
drug treatments, screening is an
important aspect of follow - up care for breast cancer patients, and early detection is critical in tailoring appropriate and effective
therapeutic interventions.
«These are
important clues as to where to look in the brain for
therapeutic effects of these
drugs,» said Derrek Hibar, first author of the paper and a professor at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute when the study was conducted.
«If we go back 10 years and ask what is the most
important parameter [to developing a
therapeutic particle], people would immediately think of the particle's size and then its surface chemistry,» says University of California, Santa Barbara, chemical engineering professor Samir Mitragotri, who develops microscopic particles of different shapes and tests their ability to deliver
drugs, but was not associated with DeSimone's study.
With genetically engineered microorganisms, such as bacteria and fungi, playing an increasing role in the green chemistry production of valuable chemical products including
therapeutic drugs, advanced biofuels and biodegradable plastics from renewables, Cas9 is emerging as an
important genome - editing tool for practitioners of synthetic biology.
«This provides an
important proof of principal that
drugs that target the stem cells could be
therapeutic.»
These forward - looking statements are based on management's current assumptions and expectations and involve risks, uncertainties and other
important factors, specifically including those relating to Lexicon's ability to successfully conduct preclinical development of its
drug candidates and advance such candidates into clinical development, achieve its operational objectives, obtain patent protection for its discoveries and establish strategic alliances, as well as those relating to manufacturing, the regulatory process, intellectual property rights, and the
therapeutic or commercial value of its
drug candidates, that may cause Lexicon's actual results to be materially different from any future results expressed or implied by such forward - looking statements.
Dr. Aldred's lab will evaluate a new
therapeutic approach known as nonsense readthrough, testing two
drugs that may be able to correct genetic defects in an
important cell - signaling pathway.
It seems to me that knowing how the
drug works, how it acts on a
therapeutic target, is an
important consideration in prioritizing potential treatments.
The project has the potential to provide
important new information about mechanisms of
drug resistance in melanoma - a key medical problem - as well as to evaluate the potential of splicing inhibitors as a
therapeutic approach in two groups of melanoma pts with different response kinetics.
«The tenfold increase of circulation time in the body is
important in
drug development and paves the way towards clinical trials of RNA nanoparticles as
therapeutic drugs.»
«An
important next step will be testing this
drug in other types of cancer and with other
therapeutic combinations,» says Shaw, who is deputy director of Salk's NCI - Designated Cancer Center.
Carmot is using Chemotype Evolution to identify and optimize innovative
drugs for challenging
therapeutic targets, thereby addressing
important unmet chemical needs.
Researchers report a surprising mechanism through which an
important new candidate
drug against leukemia exerts its
therapeutic effect...
Since these formulations have been especially titrated to the smallest possible unit of measure to identify the minimum amount of
drug that can elicit the most
therapeutic response without creating unnecessary adverse reaction, obtaining the actual and accurate weight of your pet is very
important.