Based on that, to increase
mitochondrial density, you would have to upregulate the expression of AMPK (for
mitochondrial biogenesis) and force your body to
improve its functioning i.e. become better at bioenergetics (create energy from within).
● Increased Capillarization ● Increased
Mitochondrial Density ● Parasympathetic Driver ●
Improved Oxygen Utilization Within The Muscles ● Increased Aerobic Capacity ● Increased Recovery Between Sets or Intervals ● Increases Recovery Between Workouts ● Reduces Resting Heart Rate ● Can Increase Time to Fatigue During Skill Acquisition — More focused training
There is INSUFFICIENT EVIDENCE [2,3,5] abut the effectiveness of creatine in the prevention or treatment of age related muscle loss, bipolar disorder, breathing problems during sleeping (apnea) in infants, chronic obstructive pulmonary disease (COPD), coronary artery disease, dehydration, depression, dermatomyositis, diabetes mellitus type 2, fibromyalgia, heart attack, hereditary motor sensory neuropathy, high cholesterol, HIV / AIDS - related muscle wasting, Huntington's disease, McArdle disease,
mitochondrial myopathies, multiple sclerosis, muscle cramps, orthostatic hypotension, osteoarthritis, Parkinson's disease [8], Rett syndrome, polymyositis, rheumatoid arthritis, schizophrenia, skin aging, traumatic brain injury or vision loss due to gyrate atrophy of the retina or in
improving bone
density, memory or cognitive function.