Important reports from the Weiner lab include the first DNA vaccine studied for HIV as well as for cancer immune therapy of cutaneous T cell lymphoma, the early development of DNA encoded genetic adjuvants, including IL - 12, advances in gene optimization, and advances in electroporation technologies resulting in
improved gene delivery.
Not exact matches
The team now plans to
improve their
gene -
delivery technique in an attempt to reach an even greater proportion of hair cells.
«
Gene therapy restores hearing in deaf mice, down to a whisper:
Improved delivery vector better penetrates the inner ear, also restores balance in a mouse model of Usher syndrome.»
Muscle biologists Qi Long Lu and Terence Partridge at the Medical Research Council Clinical Sciences Centre in London, U.K., and their colleagues decided to combined the antisense strategy with a chemical often used in
gene therapy because it is known to
improve delivery of DNA into cells.
NGF is in fact viewed as a viable target for AD clinical trials with one group investigating NGF ex vivo
gene delivery in a Phase 1 trial with human patients aimed at stimulating cholinergic function and
improving memory [123].
The program will be packed with papers on biochromatography, downstream processing, QbD, monoclonal antibodies, plasmids, enzymes, vaccines, viral vectors for
gene delivery, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, peptides, proteins, oligonucleotides, APIs, natural products, batch, multi-column and continuous SMB processes, column technology and equipment, monoliths, new and
improved stationary phases, membrane chromatography, regulatory aspects, and more!
Physical Methods for
Gene Transfer:
Improving the Kinetics of
Gene Delivery into Cells.
«Research topics vary from
improving corneal wound healing with new proteins to
gene delivery targeting retinal disease,» she said.