The confusion with autophagy when it comes to cancer and cancer treatment was recently summed up quite nicely with the title of an important article6
in Clinical Cancer Research: «A Matter of Life or Death (or Both): Understanding Autophagy in Cancer».
The ECCO - AACR - EORTC - ESMO Workshop on Methods
in Clinical Cancer Research is an educational programme that introduces junior clinical oncologists in any oncology subspecialty to the principles of good clinical trial design.
The study, a comprehensive tumor genetic analysis which revealed a new way of classifying cancers, is featured as one of the year's major achievements
in clinical cancer research and care.
He holds the Doris and Donald Fisher Distinguished Professorship
in Clinical Cancer Research and the Stanford W. Ascherman and Norman R. Ascherman Endowed Chair at UCSF.
«Altered microenvironment promotes progression of pre-invasive breast cancer: myoepithelial expression of integrin DCIS identifies high - risk patients and predicts recurrence» by Michael D Allen et al. published
in Clinical Cancer Research on Tuesday 3 December.
The article, titled «Entinostat Neutralizes Myeloid Derived Suppressor Cells and Enhances the Antitumor Effect of PD - 1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma,» was published
in Clinical Cancer Research and is available online.
The work is published
in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Their paper, «MR - guided Near Infrared Spectral Tomography Increases Diagnostic Performance of Breast MRI,» was published
in Clinical Cancer Research.
One of the most exciting recent advances
in clinical cancer research was the discovery that this subgroup of patients respond — sometimes dramatically — to a new class of drugs targeting the MAPK pathway through which BRAF signals.
In a report about their study published online Oct. 17
in Clinical Cancer Research, the researchers described minimal or zero tumor progression in mice treated with the microencapsulated 3BrPA.
The findings, published online
in Clinical Cancer Research, offer insight into helping patients assess treatment risk.
Samuel Weiss, PhD, Professor and Director of the HBI, and Research Assistant Professor Artee Luchman, PhD, and colleagues, published their work today
in Clinical Cancer Research, which is leading researchers to start a human phase I / II clinical trial as early as Spring 2015.
The study was published online
in Clinical Cancer Research.
Not exact matches
The Albert and Mary Lasker Foundation announced yesterday that it was presenting its prestigious 2017 Lasker - DeBakey
Clinical Medical
Research Award to a pair of National
Cancer Institute researchers, Douglas Lowy and John Schiller, who created a vaccine to prevent human papilloma virus, or HPV, from taking hold
in the body.
Among them: «a lack of data standards
in treating
cancer, lack of data sharing
in the
research and development enterprise, lack of patient input and participation
in clinical trials,» and more.
«Through this collaboration with the
cancer community's leading
clinical and pathology experts, thousands of more patients can potentially benefit from the world's growing body of knowledge about this disease,» said IBM
Research and Cognitive Solutions senior vice president John Kelly
in a statement.
The company points to a simple resource allocation problem that's hindered the most effective patient care: the fact that it is physically impossible for oncologists to keep track of every study, every
clinical trial, and every breakthrough
in the wildly stratified world of
cancer research.
In a statement released Tuesday, the American Society of
Clinical Oncology outlined
research tying alcohol to two types of
cancer and told Americans to drink less.
Besides randomized controlled
clinical trials, there are a number of ways researchers can study how a particular
cancer treatment is playing out
in the real world: there are retrospective studies, observational studies, and even prospective
research done using patient registries.
Like much of the
research on how diet affects health, the
research on the link between meat and
cancer has enough ambiguity that it's possible to cherry - pick a
research list that supports either position, but many reviews of
research on the best - established link between meat and
cancer — colorectal
cancer — find, as this 2014 review published
in the American Journal of
Clinical Nutrition does, that there is a convincing association between meat eating and colorectal
cancer.
Since 2008, Good Cookies like YOU have helped fund dozens of pediatric
cancer research grants, resulting
in NINE promising new treatments moving to
clinical trial, now available to children with
cancer.
Clinical studies indicate that moderate coffee consumption is benign or mildly beneficial
in healthy adults, with continuing
research on whether long - term consumption inhibits cognitive decline during aging or lowers the risk of some forms of
cancer.
Clinical studies indicate that moderate Kona consumption is benign or mildly beneficial
in healthy adults, with continuing
research on whether long - term consumption inhibits cognitive decline during aging or lowers the risk of some forms of
cancer.
In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
In 2010, researchers from the University of Michigan Comprehensive
Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor
Cancer Center published a study
in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
in the journal
Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor
Cancer Research showing that sulforaphane had the ability to kill breast
cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor
cancer stem cells
in mice and in lab cultures, and it also prevented the growth of new tumor cell
in mice and
in lab cultures, and it also prevented the growth of new tumor cell
in lab cultures, and it also prevented the growth of new tumor cells.
Clinical studies indicate that moderate coffee consumption is beneficial
in healthy adults, with continuing
research on whether long - term consumption inhibits cognitive decline during aging or lowers the risk of some forms of
cancer.
Clinical studies indicate that moderate Kona consumption is benign or mildly beneficial
in healthy adults, with continuing online
research on whether long - term consumption inhibits cognitive decline during aging or lowers the risk of some forms of
cancer.
At Nationwide Children's, we help kids everywhere and provide life - saving
research and care
in Cancer, NICU, The Heart Center, Muscular Dystrophy and all of our nationally ranked
clinical programs.
Science and Technology — Subject:
Clinical trials Witness (es): Professor Karol Sikora, Medical Director of
Cancer Partners UK and Dean, University of Buckingham Medical School and Simon Denegri, NIHR National Director for Public Participation and Engagement
in Research and Chair, INVOLVE; Tracey Brown, Managing Director, Sense About Science and Dr Helen Jamison, Deputy Director, Science Media Centre; Sir Kent Woods, Chief Executive,, Dr Janet Wisely, Chief Executive, Health
Research Authority, Bill Davidson, Acting Deputy Director and Head of
Research Standards and Support, Department of Health and Peter Knight, Deputy Director, Head of
Research Information and Intelligence, Department of Health Location: Room 8, Palace of Westminster
The facility is involved
in drug development and conducts
clinical research for
cancer treatment.
«
Cancer Research UK scientists first discovered abiraterone and subsequently played a key role
in its development, including funding the first
clinical trials.
These attention - getting stories about
cancer immunotherapy underline the vast career opportunities
in academic,
clinical, and industry
research for those entering this field.
In light of the results, the CNIO Breast Cancer Clinical Research Unit has already launched a large - scale Phase II Clinical Trial to validate the results in a large group of patient
In light of the results, the CNIO Breast
Cancer Clinical Research Unit has already launched a large - scale Phase II
Clinical Trial to validate the results
in a large group of patient
in a large group of patients.
«These results indicate that
clinical use of morphine could potentially be harmful»
in some
cancer patients, the scientists wrote in 2002 in Cancer Res
cancer patients, the scientists wrote
in 2002
in Cancer Res
Cancer Research.
«Several major advances
in recent years have been good news for multiple myeloma patients, but those new drugs only target terminally differentiated
cancer cells and thus can only reduce the bulk of the tumor,» said Jamieson, who is also deputy director of the Sanford Stem Cell Clinical Center, director of the CIRM Alpha Stem Cell Clinic at UC San Diego and director of stem cell research at Moores Cancer Center at UC San Diego H
cancer cells and thus can only reduce the bulk of the tumor,» said Jamieson, who is also deputy director of the Sanford Stem Cell
Clinical Center, director of the CIRM Alpha Stem Cell Clinic at UC San Diego and director of stem cell
research at Moores
Cancer Center at UC San Diego H
Cancer Center at UC San Diego Health.
Writing
in the current issue of the journal
Cancer Research, the team notes, however, that a combination of therapies will most likely be required to obtain significant
clinical results.
The results were published recently
in the journal
Clinical Cancer Research.
HBI member V. Wee Yong, PhD and
research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of Clinical Neurosciences and the university's Southern Alberta Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are comp
research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of
Clinical Neurosciences and the university's Southern Alberta
Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are comp
Research Institute, looked at human brain tumor samples and discovered that specialized immune cells
in brain tumor patients are compromised.
A
clinical trial conducted by researchers at the Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic
clinical trial conducted by researchers at the Virginia G. Piper
Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic c
Cancer Center
Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic
Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics
Research Institute (TGen), showed that a new drug called MM - 398, given
in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate
in patients with advanced, previously - treated pancreatic
cancercancer.
«It will be much more powerful than the antibodies,» says Timothy Chan, who does
clinical research in immunotherapy at Memorial Sloan Kettering
Cancer Center
in New York City.
In collaboration with Prof. Dr. Roland Schüle and his team at the Center of
Clinical Research of the Freiburg University Medical Center, the scientists were able to test several epigenetic inhibitors that had been newly developed by Schüle and his team on the
cancer stem cell model.
«These are not magic bullets,» says Solomon Hamburg, a
clinical professor of medicine at the UCLA School of Medicine and CEO of Tower
Cancer Research Foundation
in Beverly Hills.
She notes that biotech firms are investing heavily
in immunotherapy
research, and about 40 percent of the roughly 6,000
cancer clinical trials taking place
in the United States today include some form of immunotherapy.
Other UT Southwestern faculty members who contributed to this
research are: Dr. Boning Gao, Assistant Professor with the Hamon Center for Therapeutic Oncology Research and Pharmacology; Dr. Kimmo Hatanpaa, Associate Professor of Pathology; Dr. Kemp Kernstine, Professor of Cardiovascular and Thoracic Surgery and holder of the Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery; Dr. Yang Xie, Associate Professor of Clinical Sciences and Bioinformatics; Dr. Hong Zhu, Assistant Professor of Clinical Sciences and with the Simmons Cancer Center; Dr. Farjana Fattah, Assistant Professor with the Simmons Cancer Center and Pathology; Dr. Masaya Takahashi, Associate Professor with the Advanced Imaging Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal M
research are: Dr. Boning Gao, Assistant Professor with the Hamon Center for Therapeutic Oncology
Research and Pharmacology; Dr. Kimmo Hatanpaa, Associate Professor of Pathology; Dr. Kemp Kernstine, Professor of Cardiovascular and Thoracic Surgery and holder of the Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery; Dr. Yang Xie, Associate Professor of Clinical Sciences and Bioinformatics; Dr. Hong Zhu, Assistant Professor of Clinical Sciences and with the Simmons Cancer Center; Dr. Farjana Fattah, Assistant Professor with the Simmons Cancer Center and Pathology; Dr. Masaya Takahashi, Associate Professor with the Advanced Imaging Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal M
Research and Pharmacology; Dr. Kimmo Hatanpaa, Associate Professor of Pathology; Dr. Kemp Kernstine, Professor of Cardiovascular and Thoracic Surgery and holder of the Robert Tucker Hayes Foundation Distinguished Chair
in Cardiothoracic Surgery; Dr. Yang Xie, Associate Professor of
Clinical Sciences and Bioinformatics; Dr. Hong Zhu, Assistant Professor of
Clinical Sciences and with the Simmons
Cancer Center; Dr. Farjana Fattah, Assistant Professor with the Simmons
Cancer Center and Pathology; Dr. Masaya Takahashi, Associate Professor with the Advanced Imaging
Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal M
Research and Radiology; Dr. Bipasha Mukherjee, Assistant Professor of Radiation Oncology; Dr. Sandeep Burma, Associate Professor of Radiation Oncology; and Dr. Jonathan Dowell, Professor of Internal Medicine;
Scientists at The Institute of
Cancer Research, London, analysed 177 tumour samples from patients with stage I non-seminomatous tumours enrolled
in clinical trials through the Medical Research Council (MRC) Clinical Tria
clinical trials through the Medical
Research Council (MRC)
Clinical Tria
Clinical Trials Unit.
Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco - derived carcinogen
in cigarette smokers, researchers at the University of Pittsburgh
Cancer Institute (UPCI), partner with UPMC CancerCenter, demonstrated
in a phase II
clinical trial presented today at the American Association for
Cancer Research (AACR) Annual Meeting
in New Orleans.
UTSW co-authors include: Co-lead author Maria Winter, a
research associate; Dr. Luisella Spiga, a postdoctoral researcher; visiting fellow Lisa Büttner; graduate students Elizabeth Hughes and Caroline Gillis, all of Microbiology; Dr. Breck Duerkop, Instructor, Immunology; Cassie Behrendt, a research technician, Immunology; Dr. Lora Hooper, Professor and Chair of Immunology with appointments in Microbiology and in the Center for the Genetics of Host Defense, a HHMI Investigator and holder of the Jonathan W. Uhr, M.D. Distinguished Chair in Immunology, and the Nancy Cain and Jeffrey A. Marcus Scholar in Medical Research, in Honor of Dr. Bill S. Vowell; Dr. Luis Sifuentes - Dominguez, Instructor of Pediatrics; Dr. Kayci Huff - Hardy, clinical fellow, Internal Medicine in the Division of Digestive and Liver Diseases; Dr. Andrew Koh, Associate Professor of Pediatrics and Microbiology and in the Harold C. Simmons Comprehensive Cancer Center as well as Director of Pediatric Hematopoietic Stem Cell Transplantation at Children's Health; and Dr. Ezra Burstein, Professor of Internal Medicine and Molecular Biology and Chief of the Division of Digestive and Liver D
research associate; Dr. Luisella Spiga, a postdoctoral researcher; visiting fellow Lisa Büttner; graduate students Elizabeth Hughes and Caroline Gillis, all of Microbiology; Dr. Breck Duerkop, Instructor, Immunology; Cassie Behrendt, a
research technician, Immunology; Dr. Lora Hooper, Professor and Chair of Immunology with appointments in Microbiology and in the Center for the Genetics of Host Defense, a HHMI Investigator and holder of the Jonathan W. Uhr, M.D. Distinguished Chair in Immunology, and the Nancy Cain and Jeffrey A. Marcus Scholar in Medical Research, in Honor of Dr. Bill S. Vowell; Dr. Luis Sifuentes - Dominguez, Instructor of Pediatrics; Dr. Kayci Huff - Hardy, clinical fellow, Internal Medicine in the Division of Digestive and Liver Diseases; Dr. Andrew Koh, Associate Professor of Pediatrics and Microbiology and in the Harold C. Simmons Comprehensive Cancer Center as well as Director of Pediatric Hematopoietic Stem Cell Transplantation at Children's Health; and Dr. Ezra Burstein, Professor of Internal Medicine and Molecular Biology and Chief of the Division of Digestive and Liver D
research technician, Immunology; Dr. Lora Hooper, Professor and Chair of Immunology with appointments
in Microbiology and
in the Center for the Genetics of Host Defense, a HHMI Investigator and holder of the Jonathan W. Uhr, M.D. Distinguished Chair
in Immunology, and the Nancy Cain and Jeffrey A. Marcus Scholar
in Medical
Research, in Honor of Dr. Bill S. Vowell; Dr. Luis Sifuentes - Dominguez, Instructor of Pediatrics; Dr. Kayci Huff - Hardy, clinical fellow, Internal Medicine in the Division of Digestive and Liver Diseases; Dr. Andrew Koh, Associate Professor of Pediatrics and Microbiology and in the Harold C. Simmons Comprehensive Cancer Center as well as Director of Pediatric Hematopoietic Stem Cell Transplantation at Children's Health; and Dr. Ezra Burstein, Professor of Internal Medicine and Molecular Biology and Chief of the Division of Digestive and Liver D
Research,
in Honor of Dr. Bill S. Vowell; Dr. Luis Sifuentes - Dominguez, Instructor of Pediatrics; Dr. Kayci Huff - Hardy,
clinical fellow, Internal Medicine
in the Division of Digestive and Liver Diseases; Dr. Andrew Koh, Associate Professor of Pediatrics and Microbiology and
in the Harold C. Simmons Comprehensive
Cancer Center as well as Director of Pediatric Hematopoietic Stem Cell Transplantation at Children's Health; and Dr. Ezra Burstein, Professor of Internal Medicine and Molecular Biology and Chief of the Division of Digestive and Liver Diseases.
«However, a number of
clinical trials have suggested that both chemotherapy and radiotherapy are associated with the risk of suffering heart disease as a consequence of treatment,» says Hermann Brenner from the German
Cancer Research Center (DKFZ)
in Heidelberg.
Research teams focused on both cutaneous and uveal melanoma are fast - tracking discoveries into the
clinical setting, and bringing novel therapeutic options to patients
in the Philadelphia region,» said Karen Knudsen, Director of the Sidney Kimmel
Cancer Center.
The German biotech CureVac, for example, has brought mRNA - based vaccines for rabies and
cancer to
clinical trials, and Karikó now heads a
research team at BioNTech
in Mainz, Germany, that focuses on mRNA - based drugs.
According to the University of Utah's drug information service, 198 drug shortages had been reported
in the United States by late August this year, 15 of which are
cancer drugs required for
clinical research.