In vivo imaging of tumor - propagating cells, regional tumor heterogeneity, and dynamic cell movements
in embryonal rhabdomyosarcoma.
Not exact matches
When researchers screened a library of more than 200 drugs and related compounds for activity against
embryonal subtype tumor cells from three patients, the most promising results involved drugs that increased oxidative stress
in tumor cells.
As Gurwitsch hypothesized: «The place of the
embryonal formative process is a field, the boundaries of which,
in general, do not coincide with those of the embryo but surpass them.»
Abstract Neuroblastoma is an
embryonal neoplasm arising from the peripheral nervous system that accounts for 15 % of cancer deaths
in childhood.
Nearly 150 years ago, Julius Cohnheim first proposed the CSC hypothesis (also called the «
embryonal - rest theory») that suggested the presence of embryonic - like cancerous cell remnants
in adult tissues that can develop into cancer
in a non-spontaneous way (1).
The study focused on
embryonal rhabdomyosarcoma caused by mutations
in the Sonic Hedgehog signaling pathway and used a mouse model developed
in Hatley's laboratory.
Cross-species array comparative genomic hybridization identifies novel oncogenic events
in zebrafish and human
embryonal rhabdomyosarcoma.
It is possible that the Oct4 expression patterns that we observe is due to failure of one or more of these processes
in the complex, abnormal milieu of this
embryonal carcinoma cell line during differentiation.
In another case a 4 - month old dog was affected with
embryonal rhabdomyosarcoma of the trachea.