Sentences with phrase «in mmp»

This next article provides a good illustration of the hardware used in the MMP procedure and provides a good timeline for recovery from the procedure.

Changes in oxygen consumption and mitochondrial respiration and a drop in MMP levels were not detectable before an age of 24 months in these animals, indicating that Aß might initiate mitochondrial damage which is further accelerated by hyperphosphorylated tau.

However, fibrillar Aß preparations lead to similar decrease in MMP as oligomeric Aß, suggesting that mitochondrial dysfunction is mediated by both species in contrast to defects in long - term potentiation (LTP) where only oligomeric Aß inhibits LTP [59].

The increase in MMP - 13 activity could be triggered by oxidative stress, which is also a hallmark of diabetic peripheral neuropathy.

A significant finding was that mice deficient in MMP - 3 showed significantly better functional recovery 14 and 28 days after injury than non-deficient mice.

Taking a closer look at the groups of vulnerable motor neurons, the researchers found differences in MMP - 9 expression at the single - cell level.

Not exact matches

Before she was sworn in as head of the SBA in 2009, Mills was president of the private - equity firm MMP Group, which invested in businesses in the consumer products, food, textiles and industrial components industries.

According to a bio from Arrow Electronics, where she's a director, she's served since 1993 as the president of the Brunswick, Maine - based private equity group MMP Group and until 2007 was a founding partner in Solera Capital, a private equity partnership in New York.

Broiled salmon is also available at many Mexican restaurants for a healthy dose of omega - 3s (one of which research suggests may help protect against UV - induced skin damage) Eicosapentaenoic acid inhibits UV - induced MMP - 1 expression in human dermal fibroblasts.

Sims» speech also sets out the ACCC's activities in relation to a number of areas of competition law (cartels, anti-competitive agreements and practices, MMP (noting the ACCC has «about» 10 in depth investigations underway)-RRB- and touches on the Harper Review and Murray Report as well as key issues surrounding privatisation, communications and water.

Competition issues in Qld (Competitive neutrality, electricity, supermarket dominance, insurance, tender process, hospital licencing laws»), improving environment for small business (unfair contract provisions, MMP and creeping acquisitions), improving small business competitiveness.

Competition policy (SME focus; need for equity; treat SMEs as «consumers» when dealing with larger businesses - extend unfair terms contracts to small business; need «legal precedents or statutory definitions» as part of unconscionable conduct framework); competition laws (focus on unfair terms and unconscionable behaviour; mention of MMP but not in context of s 46; access - call for broader access; price signalling (not clear)-RRB-; administration

«Have your say» Apply ACL (stet) to small business in relation to unilateral conduct, MMP, unfair and unconscionable conduct, third line forcing [no further explanation of how law does not currently apply to small business or why extension needed]

Changes to competition laws (milk wars discussion and recommendations relating to MMP (introduce effects test), predatory pricing (recommend Minister direct ACCC to investigate Coles for breach of s 46 relating to predatory pricing), unconscionable conduct (suggest it be defined), statutory duty of good faith, unfair contract terms (seeks «recognition of the competitive disadvantage faced by farmers» and extension of unfair contract terms protection to small business), collective bargaining (seeks relaxation of public interest test for boycott approvals in agriculture markets, increase «ability for peak bodies to commence and progress collective bargaining and boycott applications» on behalf of members - and further dairy specific recommendations, ACCC divestiture power (wants ACCC to have similar divestiture powers to Comp Commission in UK - «simpler process of divestiture», ACCC monitoring powers (wants Minister to direct ACCC to use price monitoring powers to «monitor prices, costs and profits relating to the supply of drinking milk») and mandatory code of conduct (wants mandatory code and «Ombudsman with teeth to ensure compliance»)-RRB-.

Last week I started the 16th painting in the Mindful Mothering Project (MMP).

In most MMP systems, if a party loses the vote for a constituency, the votes go towards the list.

Re Germany: MMP seems like one of the better systems in active use, but just from the wikipedia page there are clear examples of minor parties not being properly represented.

Once they've been enacted by ordinary legislation - STV in Ireland and Tasmania, AV in mainland Australia, MMP in Germany, runoff ballots in France - and the voters have gotten used to the new system, no politician advocating a return to FPTP is taken seriously.)

To make a judgement, firstly look at DPR Voting and compare it firstly with «First Past the Post», and then with the «Mixed Member» systems such as AMS used in Scotland and MMP used in Germany.

Germany and New Zealand both use MMP, and the result in each case is a slightly altered version of a two - party system.

Germany also has a tradition of grand coalitions between its two main parties, but New Zealand shows the system can work even when there isn't that kind of bipartisan collaboration (as, let's be honest, there wouldn't be in a hypothetical United States with MMP).

In June 2016, the House of Commons of Canada Special Committee on Electoral Reform was formed to examine potential changes to the voting system with MMP being one of the options examined.

In August 2012, the initial report on a review of the MMP system by the Electoral Commission recommended abolishing the one electorate seat threshold, meaning a party winning an electorate seat but not crossing the 5 % threshold (which the same report recommends lowering to 4 %) is only awarded that electorate seat.

Two referendums were held during the 1990s on the issue, with MMP being adopted in 1993 and implemented in 1996.

[5] This article focuses primarily on semi-proportional implementations of MMP designed to yield moderately proportional election results, similar to the mixed systems used in the UK and referred to locally as AMS.

[7] It was the way that compensatory seats were allocated that made their report the origin of the additional member system, the term which the report also invented, which was then applied along with the much older «mixed system» by English - speaking writers on voting systems to West Germany's system and similar models until mixed member proportional (MMP) was invented for the adoption of the German system proposed for New Zealand in a royal commission report in 1986, which would explain why AMS and MMP have been used as synonyms.

These proteins, known as matrix metalloproteinases (MMPs), help cancer cells escape their original locations by cutting through proteins of the extracellular matrix, which normally holds cells in place.

These particles congregate at tumor sites, where MMPs cleave hundreds of peptides, which accumulate in the kidneys and are excreted in the urine.

Batimastat is designed to bind to zinc atoms in the active sites of all MMPs.

«Conventional drugs targeting the enzymes encoded by MMP genes have not been successful in the clinic due to adverse side effects,» said Rahme.

Griffiths also notes that emphysema, a lung disease common in smokers, is marked by a loss of connective tissue and may be related to increased MMP - 1 levels.

Apparently, one of the thousands of chemicals in tobacco causes MMP - 1 levels to go up.

Yet the same chemicals turn up over and over again: The molecule MMP is the key aroma in green tea, grapefruit, basil, and cabernet sauvignon wine; dimethyl sulfide shows up in oysters, tomato paste, «spoiled refrigerated chicken, and pinto - bean farts.»

Moradian - Oldak will couple the MMP - 20 discovery with another study published Nov. 2 in the Journal of Biomedical Engineering and Informatics, which concluded an amelogenin - chitosan hydrogel could repair early tooth decay by growing an enamel - like layer that reduces lesions by up to 70 percent.

Further, the researchers found that MMP - 9 can be detected not just in lumbar 5 neurons, but also in other types of motor neurons affected by ALS.

This suggests that inhibiting MMP - 9 in human patients with ALS should be beneficial.

Fast - fatigable neurons (which are involved in movements like jumping and sprinting and are the first to die in ALS) were found to have the most MMP - 9 protein, whereas slow neurons (which control posture and are only partially affected in ALS) had none.

The same effect on motor neuron function was seen when MMP - 9 was inactivated in SOD1 mutant mice using chemical injections or virally mediated gene therapy.

Columbia University Medical Center (CUMC) researchers have identified a gene, called matrix metalloproteinase - 9 (MMP - 9), that appears to play a major role in motor neuron degeneration in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

The authors hope that this study will encourage companies to explore clinical testing of such drugs — or other modes of MMP - 9 inhibition — in patients with ALS.

«Recognizing MMP - 20's function in biomineralization is one of the first steps to learning how dental enamel forms in nature,» said Qichao Ruan, lead author of the hydrogel study and a postdoctoral research associate in the Center for Craniofacial Molecular Biology at USC.

In another experiment, the researchers tested whether MMP - 9 has a functional role in ALS by crossing MMP - 9 knockout mice with SOD1 mutant mice (a standard mouse model of ALSIn another experiment, the researchers tested whether MMP - 9 has a functional role in ALS by crossing MMP - 9 knockout mice with SOD1 mutant mice (a standard mouse model of ALSin ALS by crossing MMP - 9 knockout mice with SOD1 mutant mice (a standard mouse model of ALS).

Progeny from this cross with no MMP - 9 exhibited an 80 - day delay in loss of fast - fatigable motor neuron function and a 25 percent longer lifespan, compared with littermates with two copies of the MMP - 9 gene.

MMP - 9 controls onset of paralysis in ALS mice.

MMPs cleave the peptides to liberate tiny reporter fragments, which are then filtered out by the kidney and concentrated in the urine, where they can be detected using various methods, including a simple paper - based test.

«Most MMPs are made by cells that surround and support a tumor, not by the tumor itself, as we see in pancreatic cancer,» Dr. Radisky says.

They detected the presence of an enzyme that can induce tumor metastasis, MMP - 2 (matrix metalloproteinase - 2) in mice with cancer.

However, in the presence of the cancer, the linker is cleaved by MMP - 2, which cause the two materials to be separated and the MRI signal switched «ON.»

In particular, researchers know that collagen is broken down by a certain class of enzymes called matrix metalloproteinases (MMPs), but exactly how they did this remained somewhat of a mystery, until now.

MMP - 3 immunoreactivity was detected in cells within the lesion site, invading neutrophils, and blood vessel endothelial cells in the area outside of the initial injured area (the penumbra).