Sentences with phrase «in a culture dish»

When looking at the bone cells in a culture dish, the receptor deficient mice did show 80 percent less lipid storage than regular mouse models of aging.

The researchers showed the results of this unique drug on cells growing in culture dishes and in tumors growing in mice.

They could make heart cells divide in a culture dish.

This information could then be used to prompt embryonic stem cells to differentiate in the culture dish into neurons for potential use in cell - replacement therapy.

The antibodies were able to trigger parasite - killing reactions in culture dishes as well as in mice with the parasite.

One simply can not replicate the cellular complexity of a whole organism in a culture dish.

The scientists explored this possibility in mouse neurons grown in culture dishes.

The researchers then treated SCID T cells in a culture dish with a mixture of the DNA patch and the molecular scissors.Preliminary results look promising.

This is basically tweaking the molecules: making small chemical changes to the compound in hopes of finding something that could block the growth of blood vessel cells initially in the culture dish without having toxic effects on other cell types.

They then grew the mammary buds in culture dishes for five days.

Embryonic stem cells from mice can spontaneously form the precursors of sperm in a culture dish, scientists report this week.

When these stem cells were removed from the mice and grown in a culture dish without their niche cells, they gave rise to «mini-intestines» much more readily than intestinal stem cells from mice on a normal diet.

In 2000 Michael Elowitz, now 38, designed a genetic circuit that made E. coli blink in a culture dish.

In a culture dish microglia that were modified to make a lot of TREM2 gobbled more amyloid and removed more dying neurons, compared with microglia having less of the protein.

Wang selected good lycopene producers by growing 100,000 of the strains he had created in culture dishes and simply picking out the brightest red colonies.

They studied H. pylori bacteria in a culture dish and compared the effect of only the antibiotic metronidazole against the bacteria versus the prodrug system with metronidazole and carbon monoxide combined.

And the laboratory procedure of ART itself, during which eggs, sperm and embryos are typically sucked in and out of pipettes and left to sit in culture dishes, concerns some researchers and potential parents alike.

But observing what goes wrong when a gene is missing is easier than learning to orchestrate differentiation in a culture dish.

CELLS GONE WILD Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out - of - control cell growth (left panel, pink).

To Deisseroth's elation, the effort was a success: As Boyden poked the electrode into the cell, Deisseroth saw pulses of bright blue light in the culture dish and spikes precisely matching those pulses on the computer screen.

The patient, already in a wheelchair, visited the lab and watched in amazement as his own muscle cells beat in a culture dish after corrective editing.

The two newly reported cell lines developed into several types of tissue in culture dishes, including heart and brain, and when injected into mice generated teratomas (tumors made of the three embryonic tissue types).

In a development that could alter the ethical landscape surrounding human embryonic stem (ES) cells, scientists have found that mouse ES cells can develop into oocytes in culture dishes.

Benjamin Reubinoff, Tamir Ben - Hur, and their colleagues at Hadassah University Hospital in Jerusalem, Israel, and Monash University in Melbourne, Australia, took a simpler approach, letting the stem cells multiply in a culture dish until they differentiated on their own.

Normally, CD4 cells will start dividing when they are treated with certain proteins in a culture dish.

To test that idea, Brunet and colleagues placed males in culture dishes for 2 days, and then removed them and added hermaphrodites.

As evidence, he cites a small study in 2002 on the effect of vitamin C on precancerous cells living in culture dishes.

Bailey now uses imaging technology to observe the changes in the synaptic connections in single motor neurons, as they are subjected to physiological stimulation in a culture dish.

In this process, a couple's sperm and eggs are fertilized in a culture dish.

The colonies were fixed in culture dishes with 4 % paraformaldehyde in phosphate - buffered saline (0.01 M PBS, pH 7.4) for 20 min at room temperature (RT) followed by washing with PBS (2 × 5 min).

Testicular tissue exposed to painkillers in a culture dish had around a quarter fewer sperm - producing cells after exposure to paracetamol or ibuprofen.

The cell types involved in diabetes — the beta and immune cells — are being studied in the culture dish, as well as transplanted into lab animals.

In a study published earlier this year, the same Belmonte and Gage lab team demonstrated that a few ES cells in a culture dish tended to lose stemness and evolve into muscle cell precursors, most likely goaded by a muscle differentiation factor known as BMP.

After a very extended childhood spent dividing in a culture dish, even stem cells tend to grow up and assume adult roles as workaday nerve, muscle, or blood cells, never to return to their youthful state.

The researchers showed that inhibiting SIRT1 increased levels of both the acetylated tau and the p - tau in neurons grown in culture dishes.

The connection makes sense: In IVF, the embryo is left to divide initially in a culture dish, and «without realizing it,» Temple believes, «you take away some of these essential proteins or don't provide the environment [the embryo] needs to maintain these very crucial marks» governing gene expression.

Kilian's group specializes in tissue engineering to create models of tumors, in order to more accurately study cancer processes in a culture dish.

Researchers in Japan have made fertile mammalian sperm in a culture dish, a feat long thought to be impossible.

Moving forward, he was able to place these taste stem cells in a culture dish and prompt them to grow into the different mature taste cell types, thus creating a taste bud in a dish — scientifically known as taste organoids.

When cells from most animals are grown in a culture dish, they divide until they form a single layer of cells covering the base of the dish.

In one study, published today in PLoS ONE, the researchers grew rat neurons in a culture dish and then attached them to a sheet of stretchy polymer.

Neuroscientist Ron McKay, of the National Institutes of Neurological Disorders and Stroke in Bethesda, Maryland, and other researchers have figured out how to grow dopamine - producing cells from embryonic stem cells in culture dishes, but with Isacson's method, «you just take cells and put them in the brain,» says McKay.

The researchers, led by University of California, San Diego neuroscientist Mark Tuszynski, took skin cells from the patients, grew them up in a culture dish and genetically engineered them to make human nerve growth factor (NGF).

One major roadblock, Miglietta told me, is that most of the work on transcription factors has been done on cells grown in a culture dish.

The investigators studied application of various doses of a common PBDE flame retardant on human adrenal cells in culture dishes and compared the effects with those of only the vehicle, the inactive substance used to deliver the chemical.

Investigations into human brain development using human cells in the culture dish have so far been very limited: the cells in the dish grow flat, so they do not display any three - dimensional structure.

Sheltzer, who began his project in the laboratory of Dr. Angelika Amon at MIT and carried it to conclusion in his own research group at CSHL, placed two sets of otherwise identical cells in culture dishes, side by side.

The Geron group also showed that the death - defying cells fail to form tumors, either in culture dishes or in susceptible mice.

They have spread lies about his methods, accused him of electrocuting monkeys when in fact he was working with cells in culture dishes, and limited his job opportunities.